P Boix-Montesinos, PM Soriano-Teruel… - Advanced drug delivery …, 2021 - Elsevier
Even given recent advances in nanomedicine development of breast cancer treatment in recent years and promising results in pre-clinical models, cancer nanomedicines often fail at …
Low drug bioavailability, which is mostly a result of poor aqueous drug solubilities and of inadequate drug dissolution rates, is one of the most significant challenges that …
O Maksimenko, J Malinovskaya, E Shipulo… - International journal of …, 2019 - Elsevier
Brain delivery of drugs by nanoparticles is a promising strategy that could open up new possibilities for the chemotherapy of brain tumors. As demonstrated in previous studies, the …
Simple Summary Although conventional anti-cancer drugs have been the footstone in the fight against cancer, yet they are far from optimal due to issues related with indiscriminate …
B Flühmann, I Ntai, G Borchard, S Simoens… - European Journal of …, 2019 - Elsevier
Nanomedicines, since the approval of the first one in the 1950s, have been accompanied by expectations of higher efficiency and efficacy, compared to less complex drugs. The …
In the present study, different effective parameters (temperature, reaction time, and pH) on the synthesis of quercetin‐assisted silver nanoparticles (QE‐AgNPs) are optimized. These …
Nanomedicine is an interdisciplinary research field that results from the application of nanotechnology to medicine and has the potential to significantly improve some current …
Bioactive rutin molecule has high-volume applications in food and pharmaceutical products. A considerable problem is its poor water solubility and low bioavailability. In this study …
M Rawal, A Singh, MM Amiji - Pharmaceutical research, 2019 - Springer
The purpose of this review is to discuss the challenges associated with the development of nanoparticle-based quality drug products in adhering to the principles of quality by design …