Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

The human gene catalogue is essentially complete, but we lack an equivalently vetted
inventory of bona fide human enhancers. Hundreds of thousands of candidate enhancers …

Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …

The central dogma of gene expression is that DNA is transcribed into messenger RNAs,
which in turn serve as the template for protein synthesis. The discovery of extensive …

There are two classes of glucose transporters involved in glucose homeostasis in the body,
the facilitated transporters or uniporters (GLUTs) and the active transporters or symporters …

Many prokaryotic species generate hydrogen sulfide (H2S) in their natural environments.
However, the biochemistry and physiological role of this gas in nonsulfur bacteria remain …

The human genome holds an extraordinary trove of information about human development,
physiology, medicine and evolution. Here we report the results of an international …

As vertebrate genome sequences near completion and research refocuses to their analysis,
the issue of effective genome annotation display becomes critical. A mature web tool for …

A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human
genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion …

Analyzing vertebrate genomes requires rapid mRNA/DNA and cross-species protein
alignments. A new tool, BLAT, is more accurate and 500 times faster than popular existing …