Maintenance of hydromineral balance (HB) is an essential condition for life activity at
cellular, tissue, organ and system levels. This activity has been considered as a function of …

Studies on the interactions between astrocytes and neurons in the hypothalamo-
neurohypophysial system have significantly facilitated our understanding of the regulation of …

Aim Glial fibrillary acidic protein (GFAP) molecularly associates with aquaporin 4 (AQP4) in
astrocytic plasticity. Here, we further examined how AQP4 modulates osmotic effects on …

Due to the relatively high permeability to water of the plasma membrane, water tends to
equilibrate its chemical potential gradient between the intra and extracellular compartments …

Hyponatremia due to elevated arginine vasopressin (AVP) secretion increases mortality in
liver failure patients. The mechanisms causing dysregulation of AVP secretion are unknown …

The expression of the gene encoding the RNA binding protein Caprin-2 is robustly
upregulated by dehydration in the hypothalamic supraoptic nucleus (SON). Caprin-2 has …

Gonadotropin releasing hormone (GnRH) is the decapeptide controlling sexual maturation
and adult reproductive function (Boehm et al., 2015). In the rodent hypothalamus, most cell …

O íon sódio figura como elemento chave na regulação do balanço hidroeletrolítico, de forma
que seus níveis devem ser mantidos numa estreita faixa compatível com a vida. Para tal …

Dilutional hyponatremia due to elevated arginine vasopressin (AVP) secretion increases
mortality in patients with liver failure. The neural mechanisms causing dysregulation of AVP …

This dissertation addresses the regulatory mechanisms of arginine vasopressin (AVP)
secretion during salt loading (SL) and liver failure. The experiments focused on AVP …