Over the past several decades, the incidence of bacterial meningitis in children has
decreased but there remains a significant burden of disease in adults, with a mortality of up …

Bacterial meningitis is a severe infectious disease of the membranes lining the brain
resulting in a high mortality and morbidity throughout the world. In the past decades the …

The outcome of bacterial meningitis critically depends on the rapid initiation of bactericidal
antibiotic therapy and adequate management of septic shock. In community-acquired …

Importance The impact of vaccination, antibiotics, and anti-inflammatory treatment on
pathogen distribution and outcome of bacterial meningitis over the past century is uncertain …

How to cite this article: Khilnani GC, Zirpe K, Hadda V, Mehta Y, Madan K, Kulkarni A,
Mohan A, Dixit S, Guleria R, Bhattacharya P. Guidelines for Antibiotic Prescription in …

Risk assessment of central nervous system (CNS) infection patients is of key importance in
predicting likely pathogens. However, data are lacking on the epidemiology globally. We …

Data in the literature regarding the factors that predict unfavorable outcomes in adult
herpetic meningoencephalitis (HME) cases are scarce. We conducted a multicenter study in …

Background Severe community-acquired pneumococcal meningitis is a medical emergency.
The aim of the present investigation was to evaluate the epidemiology, management and …

Background Streptococcus pneumoniae is an important cause of microbial disease in
humans. The introduction of multivalent vaccines has coincided with a dramatic decrease in …

Objective: To assess the performance of cerebrospinal fluid (CSF) lactate as a biomarker to
differentiate bacterial meningitis from viral meningitis in children, and to define an optimal …