It has been 15 years since the birth of human induced pluripotent stem cell (iPSC)
technology in 2007, and the scope of its application has been expanding. In addition to the …

The complexity of the human brain poses a substantial challenge for the development of
models of the CNS. Current animal models lack many essential human characteristics (in …

The common marmoset (Callithrix jacchus), a small New World primate, is receiving
substantial attention in the neuroscience and biomedical science fields because its …

Over a decade of schizophrenia research using human induced pluripotent stem cell (iPSC)-
derived neural models has provided substantial data describing neurobiological …

Simple Summary Multielectrode array technology allows researchers to record the
spontaneous firing activity of cultured neurons over a period of multiple weeks or months …

Schizophrenia (SCZ) is a complex, heritable and polygenic neuropsychiatric disease, which
disables the patients as well as decreases their life expectancy and quality of life. Common …

Schizophrenia (SZ) is a severe psychiatric disorder, with a prevalence of 1–2% world-wide
and substantial health-and social care costs. The pathology is influenced by both genetic …

Abstract Purpose of Review We review the ways in which stem cells are used in psychiatric
disease research, including the related advances in gene editing and directed cell …

Reelin is an extracellular matrix protein that is mainly produced in Cajal-Retzius cells and
controls neuronal migration, which is important for the proper formation of cortical layers in …

A common pathological hallmark of several neurodegenerative diseases, including
amyotrophic lateral sclerosis, is cytoplasmic mislocalization and aggregation of nuclear RNA …