In recent years, bone loss and its associated diseases have become a significant public
health concern due to increased disability, morbidity, and mortality. Oxidative stress and …

There is a vast pre-clinical literature suggesting that certain nutraceuticals have the potential
to aid the preservation of bone mass in the context of estrogen withdrawal, glucocorticoid …

Bone marrow-derived mesenchymal stem cells (BMSCs) are commonly used seed cells,
and BMSC-derived primed cartilage templates have been shown to achieve bone …

The transcription factor runt-related protein 2 (RUNX2) has an important impact on the
transformation of bone marrow mesenchymal stem cells to osteoblasts. Further studies have …

Oxidative and dicarbonyl stress, driven by excess accumulation of glycolytic intermediates in
cells that are highly permeable to glucose in the absence of effective insulin activity, appear …

RT-qPCR is the gold standard and the most commonly used method for measuring gene
expression. Selection of appropriate reference gene (s) for normalization is a crucial part of …

Background Long non-coding RNA (lncRNA) RUSC1-AS1 has been found to modulate
several cancers development. In this study, we explored the role of RUSC1-AS1 on …

Background Visceral obesity and the metabolic syndrome that often accompanies it are
robust and well-established risk factors for postmenopausal breast cancer. This increased …

Osteosarcoma is the most common malignant tumor of bone, with rapid progressive growth,
early distant metastases, and frequent recurrence after surgical treatment. Osteosarcoma is …

Osteosarcoma is the most prevalent bone malignant tumor with a high mortality rate among
children and adolescents (10–19 years of age). The Aryl Hydrocarbon Receptor (AHR) is a …