Effects of cortisol, epinephrine, and bisphenol contaminants on the transcriptional landscape of marine mammal blubber

L Kashiwabara, L Pirard, C Debier… - American Journal …, 2023 - journals.physiology.org
Top ocean predators such as marine mammals are threatened by intensifying
anthropogenic activity, and understanding the combined effects of multiple stressors on their …

Blubber transcriptome responses to repeated ACTH administration in a marine mammal

JS Deyarmin, MC McCormley, CD Champagne… - Scientific reports, 2019 - nature.com
Chronic physiological stress impacts animal fitness by catabolizing metabolic stores and
suppressing reproduction. This can be especially deleterious for capital breeding carnivores …

Intracellular negative feedback mechanisms in blubber and muscle moderate acute stress responses in fasting seals

JG Avalos, ER Piotrowski, AD Northey… - Journal of …, 2023 - journals.biologists.com
Animals may limit the cost of stress responses during key life history stages such as
breeding and molting by reducing tissue sensitivity to energy-mobilizing stress hormones …

Measuring and validating concentrations of steroid hormones in the skin of bottlenose dolphins (Tursiops truncatus)

T Bechshoft, AJ Wright, B Styrishave… - Conservation …, 2020 - academic.oup.com
A previously published analytical method demonstrated the quantification of the hormone
cortisol in cetacean skin. However, little is known about the transfer of hormones between …

Ex vivo and in vitro methods as a platform for studying anthropogenic effects on marine mammals: four challenges and how to meet them

JM Vazquez, JI Khudyakov, CB Madelaire… - Frontiers in Marine …, 2024 - frontiersin.org
Marine mammals are integral to global biodiversity and marine health through their roles in
coastal, benthic, and pelagic ecosystems. Marine mammals face escalating threats from …

A blubber gene expression index for evaluating stress in marine mammals

L Pujade Busqueta, DE Crocker… - Conservation …, 2020 - academic.oup.com
Evaluating the impacts of anthropogenic disturbance on free-ranging marine mammal
populations, many of which are in decline, requires robust diagnostic markers of …

The plasma proteome reveals markers of recent and repeated stress in free-ranging seals

JG Avalos, CD Champagne, DE Crocker… - Conservation …, 2024 - academic.oup.com
Animals in nature potentially experience multiple stressors, and those of anthropogenic
origin are likely to be repeated or chronic. However, stress hormone levels are highly …

Climate variability and life history impact stress, thyroid, and immune markers in California sea lions (Zalophus californianus) during El Niño conditions

EJ DeRango, KC Prager, DJ Greig… - Conservation …, 2019 - academic.oup.com
Wildlife is exposed to a diverse set of extrinsic and intrinsic stressors, such as climatic
variation or life history constraints, which may impact individual health and fitness. El Niño …

Elephant seal muscle cells adapt to sustained glucocorticoid exposure by shifting their metabolic phenotype

JM Torres-Velarde, SRR Kolora… - American Journal …, 2021 - journals.physiology.org
Elephant seals experience natural periods of prolonged food deprivation while breeding,
molting, and undergoing postnatal development. Prolonged food deprivation in elephant …

Adrenal response to ACTH challenge alters thyroid and immune function and varies with body reserves in molting adult female northern elephant seals

AD Northey, RR Holser, GT Shipway… - American Journal …, 2023 - journals.physiology.org
Intrinsic stressors associated with life-history stages may alter the responsiveness of the
hypothalamic-pituitary-adrenal axis and responses to extrinsic stressors. We administered …