Metabolomics: A scoping review of its role as a tool for disease biomarker discovery in selected non-communicable diseases

AV Aderemi, AO Ayeleso, OO Oyedapo, E Mukwevho - Metabolites, 2021 - mdpi.com
Metabolomics is a branch of 'omics' sciences that utilises a couple of analytical tools for the
identification of small molecules (metabolites) in a given sample. The overarching goal of …

The role of sample preparation in multidimensional gas chromatographic separations for non‐targeted analysis with the focus on recent biomedical, food, and plant …

FA Franchina, D Zanella, LM Dubois… - Journal of Separation …, 2021 - Wiley Online Library
In this review, we consider and discuss the affinity and complementarity between a generic
sample preparation technique and the comprehensive two‐dimensional gas …

The functions of Ca2+/calmodulin-dependent protein kinase II (CaMKII) in diabetes progression

K Benchoula, A Mediani, WE Hwa - Journal of Cell Communication and …, 2023 - Springer
The increase in blood glucose causes a myriad of pathways and molecular components to
malfunction, leading to diabetes. Diabetes affects each organ differently by activating distinct …

Effects of the Major Structured Triacylglycerols in Human Milk on Lipid Metabolism of Hepatocyte Cells in Vitro

Y Wu, N Zhang, ZY Deng, H Zhang… - Journal of Agricultural and …, 2020 - ACS Publications
The effect of structured triacylglycerols [1-oleoyl-2-palmitoyl-3-linoleoylglycerol (OPL), 3-
dilinoleoyl-2-palmitoylglycerol (LPL), and 1, 3-dioleoyl-2-palmitoylglycerol (OPO)] in human …

Long-term impact of neonatal intake of oleanolic acid on the expression of AMP-activated protein kinase, adiponectin and inflammatory cytokines in rats fed with a …

MG Matumba, AO Ayeleso, T Nyakudya, K Erlwanger… - Nutrients, 2019 - mdpi.com
AMP-activated protein kinase (AMPK) is known to regulate both glucose and lipid
metabolism, which play vital roles in the development of metabolic syndrome. One way of …

[HTML][HTML] Chronic melatonin treatment improves obesity by inducing uncoupling of skeletal muscle SERCA-SLN mediated by CaMKII/AMPK/PGC1α pathway and …

D Salagre, M Navarro-Alarcón, M Villalón-Mir… - Biomedicine & …, 2024 - Elsevier
Melatonin acute treatment limits obesity of young Zücker diabetic fatty (ZDF) rats by non-
shivering thermogenesis (NST). We recently showed melatonin chronically increases the …

[HTML][HTML] CaMKII activity and metabolic imbalance-related neurological diseases: Focus on vascular dysfunction, synaptic plasticity, amyloid beta accumulation, and …

J Yong, J Song - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Metabolic syndrome (MetS) is characterized by insulin resistance, hyperglycemia, excessive
fat accumulation and dyslipidemia, and is known to be accompanied by neuropathological …

[HTML][HTML] Acute and chronic effects of high-intensity interval training (HIIT) on postexercise intramuscular lipid metabolism in rats

C Min, Z Lei, C Siyu, R Shangguan… - Physiological …, 2021 - ncbi.nlm.nih.gov
Recovery from exercise refers to the period between the end of a bout of exercise and the
subsequent return to a resting or recovered state. It is a dynamic period in which many …

Intramuscular mitochondrial and lipid metabolic changes of rats after regular high-intensity interval training (HIIT) of different training periods

R Shangguan, Z Hu, Y Luo, M Chen, X Lai… - Molecular Biology …, 2023 - Springer
Abstract Background High-intensity Interval Training (HIIT) is a time-efficient form of exercise
and has gained popularity in recent years. However, at molecular level, the understanding …

CALM1 rs3179089 polymorphism might contribute to coronary artery disease susceptibility in Chinese male: a case–control study

J Huang, S Huang, J Li, M Li, L Gong, T Li, L Gu - Genes & Genomics, 2022 - Springer
Abstract Background Calmodulin 1 (CALM1) mutations are involved in the development of
coronary artery disease (CAD). However, the relationship of CALM1 rs3179089 …