Acetylation is one of the major post-translational protein modifications in the cell, with
manifold effects on the protein level as well as on the metabolome level. The acetyl group …

Post-translational modifications (PTM) decorate proteins to provide functional heterogeneity
to an existing proteome. The large number of known PTMs highlights the many ways that …

N-terminal (Nt) acetylation is known to be a highly abundant co-translational protein
modification, but the recent discovery of Golgi-and chloroplast-resident N-terminal …

The majority of eukaryotic proteins are subjected to N-terminal acetylation (Nt-acetylation),
catalysed by N-terminal acetyltransferases (NATs). Recently, the structure of an NAT …

The vast majority of eukaryotic proteins are N‐terminally modified by one or more
processing enzymes. Enzymes acting on the very first amino acid of a polypeptide include …

Acylation of biomolecules (eg, proteins and small molecules) is a process that occurs in cells
of all domains of life and has emerged as a critical mechanism for the control of many …

So far, the annotation of translation initiation sites (TISs) has been based mostly upon
bioinformatics rather than experimental evidence. We adapted ribosomal footprinting to …

Protein N-terminal acetylation (Nt-acetylation) is an important mediator of protein function,
stability, sorting, and localization. Although the responsible enzymes are thought to be fairly …

N-terminal protein modifications correspond to the first modifications which in principle any
protein may undergo, before translation is completed by the ribosome. This class of …

Legumes and a few other plant species can establish a symbiotic relationship with nitrogen-
fixing rhizobia, which enables them to survive in a nitrogen-deficient environment. During …