Metabolomics: A way forward for crop improvement

A Razzaq, B Sadia, A Raza, M Khalid Hameed… - Metabolites, 2019 - mdpi.com
Metabolomics is an emerging branch of “omics” and it involves identification and
quantification of metabolites and chemical footprints of cellular regulatory processes in …

Plants metabolome study: Emerging tools and techniques

MK Patel, S Pandey, M Kumar, MI Haque, S Pal… - Plants, 2021 - mdpi.com
Metabolomics is now considered a wide-ranging, sensitive and practical approach to
acquire useful information on the composition of a metabolite pool present in any organism …

High resolution mass spectrometry based techniques at the crossroads of metabolic pathways

C Junot, F Fenaille, B Colsch… - Mass spectrometry …, 2014 - Wiley Online Library
The metabolome is the set of small molecular mass compounds found in biological media,
and metabolomics, which refers to as the analysis of metabolome in a given biological …

Metabolomics in plant stress physiology

A Ghatak, P Chaturvedi, W Weckwerth - Plant genetics and molecular …, 2018 - Springer
Metabolomics is an essential technology for functional genomics and systems biology. It
plays a key role in functional annotation of genes and understanding towards cellular and …

Deep metabolome annotation in natural products research: towards a virtuous cycle in metabolite identification

PM Allard, G Genta-Jouve, JL Wolfender - Current Opinion in Chemical …, 2017 - Elsevier
Highlights•LC-HRMS provides detailed, high-quality data on natural extracts
metabolomes.•Size of spectral libraries in NPs research is limited but may be increased in …

Using fragmentation trees and mass spectral trees for identifying unknown compounds in metabolomics

A Vaniya, O Fiehn - TrAC Trends in Analytical Chemistry, 2015 - Elsevier
Identification of unknown metabolites is the bottleneck in advancing metabolomics, leaving
interpretation of metabolomics results ambiguous. The chemical diversity of metabolism is …

[HTML][HTML] Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery

DB Kell, R Goodacre - Drug Discovery Today, 2014 - Elsevier
Highlights•We now have metabolic network models; the metabolome is represented by their
nodes.•Metabolite levels are sensitive to changes in enzyme activities.•Drugs hitchhike on …

Annotation of the human serum metabolome by coupling three liquid chromatography methods to high-resolution mass spectrometry

S Boudah, MF Olivier, S Aros-Calt, L Oliveira… - … of Chromatography B, 2014 - Elsevier
This work aims at evaluating the relevance and versatility of liquid chromatography coupled
to high resolution mass spectrometry (LC/HRMS) for performing a qualitative and …

MS2Analyzer: A software for small molecule substructure annotations from accurate tandem mass spectra

Y Ma, T Kind, D Yang, C Leon, O Fiehn - Analytical chemistry, 2014 - ACS Publications
Systematic analysis and interpretation of the large number of tandem mass spectra (MS/MS)
obtained in metabolomics experiments is a bottleneck in discovery-driven research. MS/MS …

[HTML][HTML] Structural diversity, biosynthetic aspects, and LC-HRMS data compilation for the identification of bioactive compounds of Lepidium meyenii

FV Carvalho, PR Ribeiro - Food Research International, 2019 - Elsevier
Lepidium meyenii is widely used as a food supplement because of its medicinal properties
and nutritional value. Several studies have described the identification of its metabolites and …