Combined GSTT1 null, GSTM1 null and XPD Lys/Lys genetic polymorphisms and their association with increased risk of chronic myeloid leukemia
Purpose Glutathione S-transferases (GSTT1 and GSTM1) are instrumental in detoxification
process of activated carcinogens. Nucleotide excision repair is carried out by DNA helicase …
process of activated carcinogens. Nucleotide excision repair is carried out by DNA helicase …
[HTML][HTML] Genetic polymorphism of GSTP1, GSTM1 and GSTT1 genes and susceptibility to chronic myeloid leukaemia
Background: The development of cancer results from an imbalance between exposure to
carcinogens and the capacity of various enzyme systems engaged in activation or in the …
carcinogens and the capacity of various enzyme systems engaged in activation or in the …
Genetic polymorphism of drug metabolism enzymes (GSTM1, GSTT1 and GSTP1) in the healthy Malian population
Y Kassogue, B Diakite, O Kassogue, I Konate… - Molecular Biology …, 2020 - Springer
Glutathione S-transferase genes, known to be highly polymorphic, are implicated in the
process of phase II metabolism of many substrates, including xenobiotics, anticancer and …
process of phase II metabolism of many substrates, including xenobiotics, anticancer and …
[HTML][HTML] Genetic Insights Into Leukemia Susceptibility in the Arab Population: A Scoping Review
A Algarni - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
As per the Global Cancer Observatory, the WHO Eastern Mediterranean region (which
includes the Arabic countries) ranks highest for age-standardized mortality rate at 4 per …
includes the Arabic countries) ranks highest for age-standardized mortality rate at 4 per …
Association Between the Individual and Combined Effects of the GSTM1 and GSTT1 Polymorphisms and Risk of Leukemia: A Meta-Analysis
T Hu, G Zhou, W Li - Frontiers in Genetics, 2022 - frontiersin.org
Background: Fourteen meta-analyses reported the individual effects of the GSTM1 and
GSTT1 polymorphisms on leukemia risk. However, over 40 studies were not included in …
GSTT1 polymorphisms on leukemia risk. However, over 40 studies were not included in …
Increased risk of acute lymphoblastic leukemia in adult patients with GSTM1 null genetic polymorphism
Purpose Glutathione S-transferases (GSTT1 and GSTM1) detoxify various endogenous and
exogenous compounds and provide cytoprotective role against reactive species. This study …
exogenous compounds and provide cytoprotective role against reactive species. This study …
The copy number variation of GSTM1 as a promising prognostic factor of oral squamous cell carcinoma
I Firigato, RVM López, OA Curioni, J De Antonio… - Oral Surgery, Oral …, 2022 - Elsevier
Objective The aim of this study was to investigate whether the copy number variation (CNV)
of GSTM1 and GSTT1 is related to the occurrence of oral squamous cell carcinoma (OSCC) …
of GSTM1 and GSTT1 is related to the occurrence of oral squamous cell carcinoma (OSCC) …
[HTML][HTML] Роль полиморфных генов GSTM и GSTT в онкогенезе и возникновении гематологических новообразований
ХЯ Каримов, ЮЮ Ассесорова - Вопросы онкологии, 2020 - cyberleninka.ru
В течение жизни человек подвергается воздействию различных ксенобиотиков, одним
из биологических эффектов которых является генотоксическое действие, приводящее к …
из биологических эффектов которых является генотоксическое действие, приводящее к …
Effects of the FOXO3a rs 4946936 gene polymorphism on the foxo3a transcription factor in chronic granulocytic leukemia patients
SO Wardhani, H Susianti, P Rahayu… - … Macedonian Journal of …, 2021 - oamjms.eu
Introduction: FOXO3a has an important role in the maintenance of leukemic stem cells. BCR-
ABL inhibition therapy by TKI dasatinib aims to reduce the phosphorylation of the …
ABL inhibition therapy by TKI dasatinib aims to reduce the phosphorylation of the …