Flavonoids as antidiabetic and anti-inflammatory agents: A review on structural activity relationship-based studies and meta-analysis

NF Shamsudin, QU Ahmed, S Mahmood… - International journal of …, 2022 - mdpi.com
Flavonoids are a group of naturally occurring polyphenolic secondary metabolites which
have been reported to demonstrate a wide range of pharmacological properties, most …

Bio-actives from natural products with potential cardioprotective properties: isolation, identification, and pharmacological actions of apigenin, quercetin, and silibinin

EM Tomou, P Papakyriakopoulou, H Skaltsa… - Molecules, 2023 - mdpi.com
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide.
As a result, pharmaceutical and non-pharmaceutical interventions modifying risk factors for …

Microfluidization trends in the development of nanodelivery systems and applications in chronic disease treatments

P Ganesan, G Karthivashan, SY Park… - International journal of …, 2018 - Taylor & Francis
Plant bioactive compounds are known for their extensive health benefits and therefore have
been used for generations in traditional and modern medicine to improve the health of …

Natural products targeting inflammation-related metabolic disorders: A comprehensive review

F Nainu, A Frediansyah, SS Mamada, AD Permana… - Heliyon, 2023 - cell.com
Currently, the incidence of metabolic disorders is increasing, setting a challenge to global
health. With major advancement in the diagnostic tools and clinical procedures, much has …

[HTML][HTML] UPLC-ESI-QTOF-MS phenolic compounds identification and quantification from ethanolic extract of Myrtus communis 'Variegatha': In vitro antioxidant and …

K Okaiyeto, N Kerebba, F Rautenbach, SK Singh… - Arabian Journal of …, 2023 - Elsevier
Global public health is seriously threatened by diabetes and its complications. Although
several synthetic drugs are currently employed for managing diabetes, however, the …

[HTML][HTML] Animal models and natural products to investigate in vivo and in vitro antidiabetic activity

MM Hasan, QU Ahmed, SZM Soad, TS Tunna - Biomedicine & …, 2018 - Elsevier
Diabetes mellitus is a chronic disease which has high prevalence. The deficiency in insulin
production or impaired insulin function is the underlying cause of this disease. Utilization of …

A Propolis‐Derived Small Molecule Tectochrysin Ameliorates Type 2 Diabetes in Mice by Activating Insulin Receptor β

J Zhang, J Wu, X Shi, D Li, S Yang… - Molecular Nutrition & …, 2024 - Wiley Online Library
Scope Propolis has been found to decrease glucose levels and increase insulin sensitivity
in type 2 diabetes. However, the active ingredient responsible for these effects and its …

Preliminary Phytochemical Screening, In Vitro Antidiabetic, Antioxidant Activities, and Toxicity of Leaf Extracts of Psychotria malayana Jack

TS Nipun, A Khatib, QU Ahmed, MHM Nasir, F Supandi… - Plants, 2021 - mdpi.com
Psychotria malayana Jack belongs to the Rubiacea and is widespread in Southeast Asian
countries. It is traditionally used to treat diabetes. Despite its potential medicinal use …

Methylation and acetylation enhanced the antidiabetic activity of some selected flavonoids: in vitro, molecular modelling and structure activity relationship-based study

QU Ahmed, MN Sarian, SZ Mat So'ad, J Latip… - Biomolecules, 2018 - mdpi.com
Flavonoids have been reported to exert antihyperglycemic effects and have potential to
enhance the current therapy options against type 2 diabetes mellitus. However, the structure …

A new sulphated flavone and other phytoconstituents from the leaves of Tetracera indica Merr. and their alpha-glucosidase inhibitory activity

AM Alhassan, QU Ahmed, J Latip… - Natural product …, 2019 - Taylor & Francis
The bioactivity guided fractionation of Tetracera indica leaves crude ethanolic extract has
afforded the isolation and characterization of six compounds including a new natural product …