Mitochondrial dysfunction and excessive inflammatory responses are both sufficient to
induce pathology in age-dependent neurodegenerations. However, emerging evidence …

Glaucoma is one of the leading causes of vision impairment worldwide. In order to further
understand the molecular pathobiology of this disease and to develop better therapies …

Background Glaucoma, the leading cause of irreversible blindness, is a retinal
neurodegenerative disease, which results from progressive apoptotic death of retinal …

Background Glaucoma is a complex, multifactorial disease characterised by the loss of
retinal ganglion cells and their axons leading to a decrease in visual function. The earliest …

Vascular endothelial growth factor A (VEGF-A) is a validated therapeutic target in several
angiogenic-and vascular permeability–related pathological conditions, including certain …

Glaucoma, the second most common cause of blindness, is characterized by a progressive
loss of retinal ganglion cells and their axons, with a concomitant loss of the visual field …

Damage to the optic nerve and the death of associated retinal ganglion cells (RGCs) by
elevated intraocular pressure (IOP), also known as glaucoma, is responsible for visual …

Glaucoma is a progressive neurodegenerative disease that frequently results in irreversible
blindness. Glaucoma causes death of retinal ganglion cells (RGCs) and their axons in the …

Increased intraocular pressure (IOP) damages the retinal ganglion cell axons as they pass
through the optic nerve head (ONH). The massive connective tissue structure of the human …

Glaucoma is a neurodegenerative disease characterized by the progressive loss of retinal
ganglion cells (RGC s). Elevated intraocular pressure (IOP) is a primary risk factor for the …