Pharmacology of α‐spinasterol, a phytosterol with nutraceutical values: A review

M Majeed, F Ahmad, L Mundkur… - Phytotherapy …, 2022 - Wiley Online Library
Abstract α‐Spinasterol is a phytosterol found in various edible and non‐edible plant
sources. The edible plant materials containing α‐spinasterol include spinach leaves …

In silico structure-based designers of therapeutic targets for diabetes mellitus or obesity: A protocol for systematic review

AFT Gomes, WF de Medeiros, GS de Oliveira… - PLoS …, 2022 - journals.plos.org
Obesity is a significant risk factor for several chronic non-communicable diseases, being
closely related to Diabetes Mellitus. Computer modeling techniques favor the understanding …

Comprehensive computational studies of naturally occurring kuguacins as antidiabetic agents by targeting visfatin

SO Famuyiwa, S Ahmad, EG Fakola, AJ Olusola… - Chemistry Africa, 2023 - Springer
Diabetes mellitus continues to be a major health concern for the global population.
Targeting visfatin has been identified as a possible channel to manage the disease …

Evaluation of the Hypoglycemic Activity of Morchella conica by Targeting Protein Tyrosine Phosphatase 1B

N Begum, A Nasir, Z Parveen, T Muhammad… - Frontiers in …, 2021 - frontiersin.org
Morchella conica (M. conica) Pers. is one of six wild edible mushrooms that are widely used
by Asian and European countries for their nutritional value. The present study assessed the …

Integrated use of ligand and structure-based virtual screening, molecular dynamics, free energy calculation and ADME prediction for the identification of potential …

B Devi, SS Vasishta, B Das, ATK Baidya, RS Rampa… - Molecular Diversity, 2024 - Springer
Protein tyrosine phosphatases (PTPs) are the group of enzymes that control both cellular
activity and the dephosphorylation of tyrosine (Tyr)-phosphorylated proteins. Dysregulation …

In silico screening of potential antidiabetic phytochemicals from Tephrosia purpurea: A polypharmacology approach

H Kashyap, G Sekhon, A Varshney… - Biomedical and …, 2024 - pubs.thesciencein.org
Diabetes mellitus is a prevalent metabolic disorder characterized by elevated blood glucose
levels, posing a significant global health challenge. This study investigates the therapeutic …

Molecular docking and pharmacokinetic prediction of potential compounds from luffa acutangula as antidiabetic candidates

R Hasan, R Herowati… - … Journal of Indonesia), 2023 - jurnalnasional.ump.ac.id
Luffa acutangula is commonly used, but its considerable potential as an alternative
treatment for diabetics with a molecular target action is not yet known. Preliminary study of …

Kuguacin: biological activities of triterpenoid from Momordica charantia—a scoping review

PH Sette-de-Souza, BAA Souza, MJF Costa… - Advances in Traditional …, 2023 - Springer
The Momordica charantia is a vegetable crop used worldwide due to its biological activities.
Investigations into the pharmacological activities of the M. charantia revealed that it …

KAJIAN IN SILICO SAMBILOTO DAN OYONG SEBAGAI TERAPI DIABETES MELITUS TIPE-2

R Hasan, RRR Bahi - 2023 - repository.penerbitwidina.com
Diabetes Melitus (DM) adalah suatu gangguan endokrin dan metabolisme kronis yang
disebabkan oleh defisiensi insulin yaitu penurunan sekresi insulin dari sel-sel beta …

Bioinformatics Study of Pioglitazone Analogues as Potential Anti-Diabetic Drugs

P Rao, G Masood, R Kusanur, V Niranjan… - Russian Journal of …, 2022 - Springer
The challenges of the twenty-first century for the pharmaceutical industry are to deliver new
and safe medicines within a short period of time. Novel drug discovery is a complex and …