Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer

RB Birge, S Boeltz, S Kumar, J Carlson… - Cell Death & …, 2016 - nature.com
Apoptosis is an evolutionarily conserved and tightly regulated cell death modality. It serves
important roles in physiology by sculpting complex tissues during embryogenesis and by …

Clearance deficiency and cell death pathways: a model for the pathogenesis of SLE

A Mahajan, M Herrmann, LE Muñoz - Frontiers in immunology, 2016 - frontiersin.org
Alterations of cell death pathways, including apoptosis and the neutrophil specific kind of
death called NETosis, can represent a potential source of autoantigens. Defects in the …

Environmental microplastics exposure decreases antioxidant ability, perturbs gut microbial homeostasis and metabolism in chicken

A Li, Y Wang, MFA Kulyar, M Iqbal, R Lai, H Zhu… - Science of The Total …, 2023 - Elsevier
The widespread presence and accumulation of microplastics (MPs) in organisms has led to
their recognition as a major global ecological issue. There is a lot of data on how MPs affect …

Combinatorial peptide libraries: mining for cell-binding peptides

BP Gray, KC Brown - Chemical reviews, 2014 - ACS Publications
The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …

Cell removal: efferocytosis

PM Henson - Annual review of cell and developmental biology, 2017 - annualreviews.org
In metazoans, removal of cells in situ is involved in larval maturation, metamorphosis, and
embryonic development. In adults, such cell removal plays a role in the homeostatic …

Deep learning and 3D-DESI imaging reveal the hidden metabolic heterogeneity of cancer

P Inglese, JS McKenzie, A Mroz, J Kinross… - Chemical …, 2017 - pubs.rsc.org
Visual inspection of tumour tissues does not reveal the complex metabolic changes that
differentiate cancer and its sub-types from healthy tissues. Mass spectrometry imaging …

Integrated application of multi-omics approach and biochemical assays provides insights into physiological responses to saline-alkaline stress in the gills of crucian …

Y Liu, M Yao, S Li, X Wei, L Ding, S Han… - Science of the Total …, 2022 - Elsevier
Given the decline of freshwater resources in recent years, the accessible space for
freshwater aquaculture is rapidly shrinking, and aquaculture in saline-alkaline water has …

Bilayer forming phospholipids as targets for cancer therapy

C Stoica, AK Ferreira, K Hannan, M Bakovic - International Journal of …, 2022 - mdpi.com
Phospholipids represent a crucial component for the structure of cell membranes.
Phosphatidylcholine and phosphatidylethanolamine are two phospholipids that comprise …

Phospholipid fingerprints of milk from different mammalians determined by 31P NMR: Towards specific interest in human health

C Garcia, NW Lutz, S Confort-Gouny, PJ Cozzone… - Food Chemistry, 2012 - Elsevier
Our objective was to identify and quantify phospholipids in milk from different species
(human HM, cow CoM, camel CaM, and mare MM) using an optimised 31P NMR …

Fusion stage of HIV-1 entry depends on virus-induced cell surface exposure of phosphatidylserine

E Zaitseva, E Zaitsev, K Melikov, A Arakelyan… - Cell host & …, 2017 - cell.com
HIV-1 entry into host cells starts with interactions between the viral envelope glycoprotein
(Env) and cellular CD4 receptors and coreceptors. Previous work has suggested that …