Primary tumor resection for metastatic colorectal, gastric and pancreatic cancer patients: In search of scientific evidence to inform clinical practice
Simple Summary Oncology practice in gastrointestinal tumors is moving toward therapeutic
algorithms comprising multiple systemic options integrated with loco-regional strategies …
algorithms comprising multiple systemic options integrated with loco-regional strategies …
The role of primary tumor resection in colorectal cancer patients with asymptomatic, synchronous, unresectable metastasis: a multicenter randomized controlled trial
We aimed to assess the survival benefits of primary tumor resection (PTR) followed by
chemotherapy in patients with asymptomatic stage IV colorectal cancer with asymptomatic …
chemotherapy in patients with asymptomatic stage IV colorectal cancer with asymptomatic …
Bevacizumab improves survival in metastatic colorectal cancer patients with primary tumor resection: A meta-analysis
D Cao, Y Zheng, H Xu, W Ge, X Xu - Scientific reports, 2019 - nature.com
It is not well determined whether primary tumor resection is associated with better outcomes
in metastatic colorectal cancer (mCRC) patients treated with bevacizumab. In this meta …
in metastatic colorectal cancer (mCRC) patients treated with bevacizumab. In this meta …
Primary tumor resection in patients with unresectable colorectal cancer with synchronous metastases could improve the activity of poly-chemotherapy: A trial-level …
GA Colloca, A Venturino, D Guarneri - Surgical oncology, 2022 - Elsevier
Introduction Primary tumor resection (PTR) in patients with metastatic unresectable
colorectal cancer is less and less used to prevent local complications. Although its …
colorectal cancer is less and less used to prevent local complications. Although its …
Elevated preoperative CA125 is associated with poor survival in patients with metastatic colorectal cancer undergoing primary tumor resection: a retrospective cohort …
JH Huang, HS Liu, T Hu, ZJ Zhang, XW He… - Gastroenterology …, 2022 - academic.oup.com
Background The impact of the preoperative carbohydrate antigen 125 (CA125) level on the
survival of metastatic colorectal cancer (CRC) patients undergoing primary tumor resection …
survival of metastatic colorectal cancer (CRC) patients undergoing primary tumor resection …
Postoperative mortality risk assessment in colorectal cancer: development and validation of a clinical prediction model using data from the Dutch ColoRectal Audit
LCF de Nes, G Hannink, J 't Lam-Boer, N Hugen… - BJS open, 2022 - academic.oup.com
Background As the outcome of modern colorectal cancer (CRC) surgery has significantly
improved over the years, however, renewed and adequate risk stratification for mortality is …
improved over the years, however, renewed and adequate risk stratification for mortality is …
Interaction between primary tumor resection, primary tumor location, and survival in synchronous metastatic colorectal cancer: a population-based study
DEW van der Kruijssen, NPM Brouwer… - American Journal of …, 2021 - journals.lww.com
Objectives: Location of the primary tumor has prognostic value and predicts the effect of
certain therapeutics in synchronous metastatic colorectal cancer. We investigated whether …
certain therapeutics in synchronous metastatic colorectal cancer. We investigated whether …
Temporal development in survival, and gender and regional differences in the Swedish population of patients with synchronous and metachronous metastatic …
E Osterlund, B Glimelius - Acta Oncologica, 2022 - Taylor & Francis
Background Survival in patients with metastatic colorectal cancer (mCRC) has markedly
improved in patients included in clinical trials. In population-based materials, improvements …
improved in patients included in clinical trials. In population-based materials, improvements …
Clinical Outcomes of Upfront Primary Tumor Resection in Synchronous Unresectable Metastatic Colorectal Cancer
JE Shin, HJ An, BY Shim, H Kim, HS Park, HM Cho… - Cancers, 2023 - mdpi.com
Simple Summary The role of upfront primary tumor resection (PTR) in patients with
unresectable synchronous metastatic colorectal cancer without severe symptoms remains …
unresectable synchronous metastatic colorectal cancer without severe symptoms remains …
Primary tumor-related complications and salvage outcomes in patients with metastatic rectal cancer and an untreated primary tumor
BACKGROUND: For rectal cancer with unresectable metastases, current practice favors
omitting interventions directed at the primary tumor in asymptomatic patients. OBJECTIVE …
omitting interventions directed at the primary tumor in asymptomatic patients. OBJECTIVE …