MicroRNAs in cancer

G Di Leva, M Garofalo, CM Croce - Annual Review of Pathology …, 2014 - annualreviews.org
MicroRNAs (miRNAs) are small noncoding RNAs that typically inhibit the translation and
stability of messenger RNAs (mRNAs), controlling genes involved in cellular processes such …

Pathogenic role of exosomes and microRNAs in HPV‐mediated inflammation and cervical cancer: a review

J Sadri Nahand, M Moghoofei… - … journal of cancer, 2020 - Wiley Online Library
Cervical cancer (CC) is the fourth most common cause of cancer death in women. The most
important risk factor for the development of CC is cervical infection with human papilloma …

The origin and functions of exosomes in cancer

C Rajagopal, KB Harikumar - Frontiers in oncology, 2018 - frontiersin.org
Exosomes are nanovesicles having a maximum size of 150 nm and is a newly emerging
focus in various fields of research. Its role in cargo trafficking along with its differential …

MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy

AL Kasinski, FJ Slack - Nature Reviews Cancer, 2011 - nature.com
In normal cells multiple microRNAs (miRNAs) converge to maintain a proper balance of
various processes, including proliferation, differentiation and cell death. miRNA …

HPV16 and HPV18 genome structure, expression, and post-transcriptional regulation

L Yu, V Majerciak, ZM Zheng - International journal of molecular sciences, 2022 - mdpi.com
Human papillomaviruses (HPV) are a group of small non-enveloped DNA viruses whose
infection causes benign tumors or cancers. HPV16 and HPV18, the two most common high …

miR‐146a‐5p: expression, regulation, and functions in cancer

JR Iacona, CS Lutz - Wiley Interdisciplinary Reviews: RNA, 2019 - Wiley Online Library
Cancer as we know it is actually an umbrella term for over 100 very unique malignancies in
various tissues throughout the human body. Each type, and even subtype of cancer, has …

Clinical implications of (epi) genetic changes in HPV-induced cervical precancerous lesions

RDM Steenbergen, PJF Snijders… - Nature Reviews …, 2014 - nature.com
Infection of cervical epithelium with high-risk human papilloma virus (hrHPV) might result in
productive or transforming cervical intraepithelial neoplasia (CIN) lesions, the morphology of …

Regulation of the MIR155 host gene in physiological and pathological processes

TS Elton, H Selemon, SM Elton, NL Parinandi - Gene, 2013 - Elsevier
MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in
posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing …

[HTML][HTML] miR-155 gene: a typical multifunctional microRNA

I Faraoni, FR Antonetti, J Cardone… - Biochimica et Biophysica …, 2009 - Elsevier
In the last years small RNA molecules, ie microRNA (miRNA) encoded by miR genes, have
been found to play a crucial role in regulating gene expression of a considerable part of …

microRNAs: new prognostic, diagnostic, and therapeutic biomarkers in cervical cancer

JS Nahand, S Taghizadeh‐boroujeni… - Journal of cellular …, 2019 - Wiley Online Library
Cervical cancer is as a kind of cancer beginning from the cervix. Given that cervical cancer
could be observed in women who infected with papillomavirus, regular oral contraceptives …