Small molecules in the treatment of COVID-19

S Lei, X Chen, J Wu, X Duan, K Men - Signal transduction and targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

Effects of COVID‐19 vaccination during pregnancy on SARS‐CoV‐2 infection and maternal and neonatal outcomes: A systematic review and meta‐analysis

M Rahmati, DK Yon, SW Lee, L Butler… - Reviews in Medical …, 2023 - Wiley Online Library
SARS‐CoV‐2 infection during pregnancy is associated with adverse maternal and neonatal
outcomes, but no systematic synthesis of evidence on COVID‐19 vaccination during …

Monkeypox outbreak 2022: What we know so far and its potential drug targets and management strategies

AA Rabaan, AH Abas, TE Tallei… - Journal of Medical …, 2023 - Wiley Online Library
Monkeypox is a rare zoonotic disease caused by infection with the monkeypox virus. The
disease can result in flu‐like symptoms, fever, and a persistent rash. The disease is currently …

[HTML][HTML] A comprehensive review on pharmacologic agents, immunotherapies and supportive therapeutics for COVID-19

K Sharun, R Tiwari, MI Yatoo, S Natesan, D Megawati… - Narra J, 2022 - ncbi.nlm.nih.gov
The emergence of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected many countries throughout …

Efficacy and safety of tixagevimab‐cilgavimab as pre‐exposure prophylaxis for COVID‐19: a systematic review and meta‐analysis

AY Soeroto, TA Yanto, A Kurniawan… - Reviews in Medical …, 2023 - Wiley Online Library
Some proportions of populations, such as immunocompromised patients and organ
transplant recipients might have inadequate immune responses to the vaccine for …

Insight into the role of clathrin‐mediated endocytosis inhibitors in SARS‐CoV‐2 infection

SS Alkafaas, AM Abdallah, S Ghosh… - Reviews in Medical …, 2023 - Wiley Online Library
Emergence of SARS‐CoV‐2 variants warrants sustainable efforts to upgrade both the
diagnostic and therapeutic protocols. Understanding the details of cellular and molecular …

Quercetin for the treatment of COVID‐19 patients: a systematic review and meta‐analysis

HA Cheema, A Sohail, A Fatima… - Reviews in Medical …, 2023 - Wiley Online Library
Currently approved therapies for COVID‐19 are mostly limited by their low availability, high
costs or the requirement of parenteral administration by trained medical personnel in an in …

Antiviral molecular targets of essential oils against SARS-CoV-2: A systematic review

M Iqhrammullah, DR Rizki, A Purnama, TF Duta… - Scientia …, 2023 - mdpi.com
Essential oils are potential therapeutics for coronavirus disease 2019 (COVID-19), in which
some of the volatile compounds of essential oils have been well known for their broad …

COVID-19 drug discovery and treatment options

JFW Chan, S Yuan, H Chu, S Sridhar… - Nature Reviews …, 2024 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused substantial morbidity and …

Repurposing molnupiravir for COVID-19: the mechanisms of antiviral activity

AJW Yip, ZY Low, VTK Chow, SK Lal - Viruses, 2022 - mdpi.com
Molnupiravir is a β-d-N4-hydroxycytidine-5′-isopropyl ester (NHC) compound that exerts
antiviral activity against various RNA viruses such as influenza, SARS, and Ebola viruses …