Toward a systems view on RNA-binding proteins and associated RNAs in plants: guilt by association
JL Mateos, D Staiger - The Plant Cell, 2023 - academic.oup.com
RNA-binding proteins (RBPs) have a broad impact on most biochemical, physiological, and
developmental processes in a plant's life. RBPs engage in an on-off relationship with their …
developmental processes in a plant's life. RBPs engage in an on-off relationship with their …
Signal-noise metrics for RNA binding protein identification reveal broad spectrum protein-RNA interaction frequencies and dynamics
JC Kristofich, CV Nicchitta - Nature Communications, 2023 - nature.com
Recent efforts towards the comprehensive identification of RNA-bound proteomes have
revealed a large, surprisingly diverse family of candidate RNA-binding proteins (RBPs) …
revealed a large, surprisingly diverse family of candidate RNA-binding proteins (RBPs) …
Noncanonical Amino Acid Incorporation in Animals and Animal Cells
JC Kim, YJ Kim, S Cho, HS Park - Chemical Reviews, 2024 - ACS Publications
Noncanonical amino acids (ncAAs) are synthetic building blocks that, when incorporated
into proteins, confer novel functions and enable precise control over biological processes …
into proteins, confer novel functions and enable precise control over biological processes …
A hybrid structure determination approach to investigate the druggability of the nucleocapsid protein of SARS-CoV-2
G Padroni, M Bikaki, M Novakovic… - Nucleic Acids …, 2023 - academic.oup.com
The pandemic caused by SARS-CoV-2 has called for concerted efforts to generate new
insights into the biology of betacoronaviruses to inform drug screening and development …
insights into the biology of betacoronaviruses to inform drug screening and development …
Specific protein-RNA interactions are mostly preserved in biomolecular condensates
T de Vries, M Novakovic, Y Ni, I Smok, C Inghelram… - Science …, 2024 - science.org
Many biomolecular condensates are enriched in and depend on RNAs and RNA binding
proteins (RBPs). So far, only a few studies have addressed the characterization of the …
proteins (RBPs). So far, only a few studies have addressed the characterization of the …
RNxQuest: An Extension to the xQuest Pipeline Enabling Analysis of Protein–RNA Cross-Linking/Mass Spectrometry Data
CP Sarnowski, M Götze, A Leitner - Journal of Proteome …, 2023 - ACS Publications
Cross-linking and mass spectrometry (XL-MS) workflows are increasingly popular
techniques for generating low-resolution structural information about interacting …
techniques for generating low-resolution structural information about interacting …
Comprehensive mapping of exon junction complex binding sites reveals universal EJC deposition in Drosophila
L Morillo, T Paternina, Q Alasseur, A Genovesio… - BMC biology, 2023 - Springer
Background The exon junction complex (EJC) is involved in most steps of the mRNA life
cycle, ranging from splicing to nonsense-mediated mRNA decay (NMD). It is assembled by …
cycle, ranging from splicing to nonsense-mediated mRNA decay (NMD). It is assembled by …
A type III-Dv CRISPR-Cas system is controlled by the transcription factor RpaB and interacts with the DEAD-box RNA helicase CrhR
R Bilger, A Migur, A Wulf, C Steglich, H Urlaub… - Cell Reports, 2024 - cell.com
How CRISPR-Cas systems defend bacteria and archaea against invading genetic elements
is well understood, but less is known about their regulation. In the cyanobacterium …
is well understood, but less is known about their regulation. In the cyanobacterium …
Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA
P Keil, A Wulf, N Kachariya, S Reuscher… - Nucleic acids …, 2023 - academic.oup.com
RNA-binding proteins (RBPs) control every RNA metabolic process by multiple protein–RNA
and protein–protein interactions. Their roles have largely been analyzed by crude mutations …
and protein–protein interactions. Their roles have largely been analyzed by crude mutations …
PRC2-RNA interactions: Viewpoint from Tom Cech, Chen Davidovich, and Richard Jenner
Diverse biochemical, structural, and in vivo data support models for the regulation of
polycomb repressive complex 2 (PRC2) activity by RNAs, which may contribute to the …
polycomb repressive complex 2 (PRC2) activity by RNAs, which may contribute to the …