Cells exert, sense, and respond to physical forces through an astounding diversity of
mechanisms. Here we review recently developed tools to quantify the forces generated by …

Cell–cell junctions are specializations of the plasma membrane responsible for physically
integrating cells into tissues. We are now beginning to appreciate the diverse impacts that …

In eukaryotic cells, organelles and the cytoskeleton undergo highly dynamic yet organized
interactions capable of orchestrating complex cellular functions. Visualizing these …

The dynamic behavior of epithelial cell sheets plays a central role during numerous
developmental processes. Genetic and imaging studies of epithelial morphogenesis in a …

During development, mechanical forces cause changes in size, shape, number, position,
and gene expression of cells. They are therefore integral to any morphogenetic processes …

Combining concepts from topology and algorithms, this book delivers what its title promises:
an introduction to the field of computational topology. Starting with motivating problems in …

Apical constriction is a cell shape change that promotes tissue remodeling in a variety of
homeostatic and developmental contexts, including gastrulation in many organisms and …

Cell migration is fundamental to establishing and maintaining the proper organization of
multicellular organisms. Morphogenesis can be viewed as a consequence, in part, of cell …

Many genes and molecules that drive tissue patterning during organogenesis and tissue
regeneration have been discovered. Yet, we still lack a full understanding of how these …

The use of genetic mutations to study protein functions in vivo is a central paradigm of
modern biology. Recent advances in reverse genetics such as RNA interference and …