Kidney and epigenetic mechanisms of salt-sensitive hypertension

W Kawarazaki, T Fujita - Nature Reviews Nephrology, 2021 - nature.com
Dietary salt intake increases blood pressure (BP) but the salt sensitivity of BP differs
between individuals. The interplay of ageing, genetics and environmental factors, including …

[HTML][HTML] Linking mitochondrial dysfunction, metabolic syndrome and stress signaling in Neurodegeneration

SK Jha, NK Jha, D Kumar, RK Ambasta… - Biochimica et Biophysica …, 2017 - Elsevier
Mounting evidence suggests a link between metabolic syndrome (MetS) such as diabetes,
obesity, non-alcoholic fatty liver disease in the progression of Alzheimer's disease (AD) …

Central sympathetic nerve activation in subarachnoid hemorrhage

Y Hasegawa, H Uchikawa, S Kajiwara… - Journal of …, 2022 - Wiley Online Library
Subarachnoid hemorrhage (SAH) is a life‐threatening condition, and although its two main
complications—cerebral vasospasm (CVS)/delayed cerebral ischemia (DCI) and early brain …

Asprosin in the paraventricular nucleus induces sympathetic activation and pressor responses via cAMP-dependent ROS production

XL Wang, JX Wang, JL Chen, WY Hao, WZ Xu… - International journal of …, 2022 - mdpi.com
Asprosin is a newly discovered adipokine that is involved in regulating metabolism.
Sympathetic overactivity contributes to the pathogenesis of several cardiovascular diseases …

[HTML][HTML] Oxytocin may have a therapeutical potential against cardiovascular disease. Possible pharmaceutical and behavioral approaches

B Buemann, K Uvnäs-Moberg - Medical hypotheses, 2020 - Elsevier
Based on the ancient role of oxytocin and its homologues as amplifiers of reproduction we
argue for an evolutionary coupling of oxytocin to signaling pathway which support …

Sensory circumventricular organs, neuroendocrine control, and metabolic regulation

JK Jeong, SA Dow, CN Young - Metabolites, 2021 - mdpi.com
The central nervous system is critical in metabolic regulation, and accumulating evidence
points to a distributed network of brain regions involved in energy homeostasis. This is …

Autonomic dysfunction and treatment strategies in intracerebral hemorrhage

K Kang, K Shi, J Liu, N Li, J Wu… - CNS Neuroscience & …, 2024 - Wiley Online Library
Aims Autonomic dysfunction with central autonomic network (CAN) damage occurs
frequently after intracerebral hemorrhage (ICH) and contributes to a series of adverse …

Chemerin-9 in paraventricular nucleus increases sympathetic outflow and blood pressure via glutamate receptor-mediated ROS generation

JX Wang, XL Wang, ZQ Xu, Y Zhang, D Xue… - European journal of …, 2022 - Elsevier
Chemerin is an adipokine involved in regulating energy homeostasis and reproductive
function. Excessive sympathetic activity contributes to hypertension, chronic heart failure and …

The stabilization of central sympathetic nerve activation by renal denervation prevents cerebral vasospasm after subarachnoid hemorrhage in rats

Y Takemoto, Y Hasegawa, K Hayashi, C Cao… - Translational stroke …, 2020 - Springer
The poor prognosis of subarachnoid hemorrhage (SAH) might be associated with
sympathetic nerve activation (catecholamine surge) initiated by hypothalamic injury. As …

Phosphorus supplementation mitigates perivascular adipose inflammation–induced cardiovascular consequences in early metabolic impairment

HS Dwaib, G Ajouz, I AlZaim, R Rafeh… - Journal of the …, 2021 - Am Heart Assoc
Background The complexity of the interaction between metabolic dysfunction and
cardiovascular complications has long been recognized to extend beyond simple …