The pathophysiology of vascular disease is linked to accelerated biological aging and a
combination of genetic, lifestyle, biological, and environmental risk factors. Within the …

Cardiac aging, particularly cardiac cell senescence, is a natural process that occurs as we
age. Heart function gradually declines in old age, leading to continuous heart failure, even in …

Atherosclerosis, characterized as the chronic inflammation of the arterial wall, is one of the
leading causes of coronary artery disease (CAD), and macrophages are found to play …

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, and
senescent cells have emerged as key contributors to its pathogenesis. Senescent cells …

Alzheimer's disease (AD) is a prevalent type of dementia in elderly populations with a
significant genetic component. The accumulating evidence suggests that AD involves a …

Abstract Purpose of Review This review summarizes the involvement of inflammaging in
vascular damage with focus on the epigenetic mechanisms by which inflammaging-induced …

Bipolar disorder (BD) has been previously associated with premature mortality and aging,
including acceleration of epigenetic aging. Suicide attempts (SA) are greatly elevated in BD …

This review will focus on epigenetic modifications utilizing the DNA methylation mechanism,
which is potentially involved in the pathogenesis of heart failure with preserved ejection …

Most pre-clinical studies in cardiac ischemia-reperfusion injury (I/R) are carried out in young
or old animals, which does not cater to the adult age in humans who encounter I/R. Not …

Background Rapid diagnosis of acute myocardial infarction (AMI) is the subject of many
clinical studies as it enables an effective therapy, preventing adverse progression of AMI …