Matrix metalloproteinase (MMP)-9 (Gelatinase B, 92-kD type IV collagenase, EC 3.4. 24.35)
is an MMP that is present in low quantities in the healthy adult lung, but much more …

The matrix metalloproteinases (MMPs), a family of 25 secreted and cell surface-bound
neutral proteinases, process a large array of extracellular and cell surface proteins under …

In healthy lung, Matrix Metalloproteinases (MMPs) and their physiological inhibitors, tissue
inhibitors of matrix metalloproteinases (TIMPs), are produced in the respiratory tract by a …

In airway diseases such as asthma and COPD, specific structural changes may be
observed, very likely secondary to an underlying inflammatory process. Although it is still …

Although histologic features of airway remodeling have been well characterized in asthma,
the immunologic and inflammatory mechanisms that drive progression of asthma to …

The procyanidin-rich maritime pine bark extract Pycnogenol has well-documented
antioxidant and anti-inflammatory activity. After oral administration of Pycnogenol two major …

Asthma is the most common chronic inflammatory disorder of the airways among children. It
is a complex clinical disease characterized by airway obstruction, airway inflammation and …

Abstract Familial Amyloidotic Polyneuropathy (FAP) is a disorder characterized by the
extracellular deposition of fibrillar Transthyretin (TTR) amyloid, with a special involvement of …

Chronic obstructive pulmonary disease (COPD) and asthma are both associated with airflow
restriction and progressive remodeling, which affect the respiratory tract. Among various …

Matrix metalloproteinases (MMPs) are a pivotal family of zinc enzymes responsible for
degradation of the extracellular matrix (ECM) components including basement membrane …