LAMP diagnostics at the point-of-care: emerging trends and perspectives for the developer community

TJ Moehling, G Choi, LC Dugan, M Salit… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Over the past decade, loop-mediated isothermal amplification (LAMP)
technology has played an important role in molecular diagnostics. Amongst numerous …

Point-of-care testing based on smartphone: The current state-of-the-art (2017–2018)

J Liu, Z Geng, Z Fan, J Liu, H Chen - Biosensors and Bioelectronics, 2019 - Elsevier
Smartphone-based point-of-care testing (POCT) is rapidly emerging as a potential
alternative to the traditional laboratory-based diagnostic testing owing to economic …

Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy

P Fozouni, S Son, MD de León Derby, GJ Knott… - Cell, 2021 - cell.com
The December 2019 outbreak of a novel respiratory virus, SARS-CoV-2, has become an
ongoing global pandemic due in part to the challenge of identifying symptomatic …

Rapid isothermal amplification and portable detection system for SARS-CoV-2

A Ganguli, A Mostafa, J Berger… - Proceedings of the …, 2020 - National Acad Sciences
The COVID-19 pandemic provides an urgent example where a gap exists between
availability of state-of-the-art diagnostics and current needs. As assay protocols and primer …

Advances in point-of-care nucleic acid extraction technologies for rapid diagnosis of human and plant diseases

R Paul, E Ostermann, Q Wei - Biosensors and bioelectronics, 2020 - Elsevier
Global health and food security constantly face the challenge of emerging human and plant
diseases caused by bacteria, viruses, fungi, and other pathogens. Disease outbreaks such …

Recent trends in smartphone-based detection for biomedical applications: a review

S Banik, SK Melanthota, Arbaaz, JM Vaz… - Analytical and …, 2021 - Springer
Smartphone-based imaging devices (SIDs) have shown to be versatile and have a wide
range of biomedical applications. With the increasing demand for high-quality medical …

Fully integrated microfluidic devices for qualitative, quantitative and digital nucleic acids testing at point of care

Z Li, Y Bai, M You, J Hu, C Yao, L Cao, F Xu - Biosensors and …, 2021 - Elsevier
Benefiting from emerging miniaturized and equipment-free nucleic acid testing (NAT)
technologies, fully integrated NAT devices at point of care (POC) with the capability of …

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

F Sun, A Ganguli, J Nguyen, R Brisbin, K Shanmugam… - Lab on a Chip, 2020 - pubs.rsc.org
Rapid, sensitive and specific detection and reporting of infectious pathogens is important for
patient management and epidemic surveillance. We demonstrated a point-of-care system …

Microfluidic devices for detection of RNA viruses

A Basiri, A Heidari, MF Nadi… - Reviews in medical …, 2021 - Wiley Online Library
There is a long way to go before the coronavirus disease 2019 (Covid‐19) outbreak comes
under control. qRT‐PCR is currently used for the detection of severe acute respiratory …

Simpler, faster, and sensitive Zika virus assay using smartphone detection of loop-mediated isothermal amplification on paper microfluidic chips

K Kaarj, P Akarapipad, JY Yoon - Scientific reports, 2018 - nature.com
The recent Zika virus (ZIKV) outbreak has prompted the need for field-ready diagnostics that
are rapid, easy-to-use, handheld, and disposable while providing extreme sensitivity and …