Solid-state NMR spectroscopy is one of the most commonly used techniques to study the
atomic-resolution structure and dynamics of various chemical, biological, material, and …

Since the first pioneering studies on small deuterated peptides dating more than 20 years
ago, 1H detection has evolved into the most efficient approach for investigation of …

Protein structure determination by proton-detected magic-angle spinning (MAS) NMR has
focused on highly deuterated samples, in which only a small number of protons are …

Magic-angle spinning solid-state NMR spectroscopy is an important technique to study
molecular structure, dynamics and interactions, and is rapidly gaining importance in …

Membrane proteins are still heavily under-represented in the protein data bank (PDB),
owing to multiple bottlenecks. The typical low abundance of membrane proteins in their …

Solid-state nuclear magnetic resonance (ssNMR) spectroscopy enables the structural
characterization of a diverse array of biological assemblies that include amyloid fibrils, non …

Spontaneous activity shifts at constant experimental conditions represent a widespread
regulatory mechanism in ion channels. The molecular origins of these modal gating shifts …

Abstract 1H detection can significantly improve solid‐state NMR spectral sensitivity and
thereby allows studying more complex proteins. However, the common prerequisite for 1H …

Building on a decade of continuous advances of the community, the recent development of
very fast (60 kHz and above) magic-angle spinning (MAS) probes has revolutionised the …

In recent years, exciting developments in instrument technology and experimental
methodology have advanced the field of magic-angle spinning (MAS) nuclear magnetic …