Extracellular vesicles as personalized medicine

DJ Beetler, DN Di Florio, KA Bruno, T Ikezu… - Molecular aspects of …, 2023 - Elsevier
Extracellular vesicles (EVs) are released from all cells in the body, forming an important
intercellular communication network that contributes to health and disease. The contents of …

Breakthrough of extracellular vesicles in pathogenesis, diagnosis and treatment of osteoarthritis

Z Liu, Y Zhuang, L Fang, C Yuan, X Wang… - Bioactive …, 2022 - pmc.ncbi.nlm.nih.gov
Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …

Smart skin‐adhesive patches: from design to biomedical applications

SHD Wong, GR Deen, JS Bates, C Maiti… - Advanced Functional …, 2023 - Wiley Online Library
With the advancement of medical and digital technologies, smart skin adhesive patches
have emerged as a key player for complex medical purposes. In particular, skin adhesive …

[HTML][HTML] Influences of age, race, and sex on extracellular vesicle characteristics

NN Hooten, AM Byappanahalli, M Vannoy… - Theranostics, 2022 - ncbi.nlm.nih.gov
Recent attention has focused on the use of extracellular vesicles (EVs) as biological
indicators of health and disease. These small, nano-sized membrane bound vesicles are …

[PDF][PDF] Neoantigen‐based cancer vaccination using chimeric RNA‐loaded dendritic cell‐derived extracellular vesicles

X Xiong, X Ke, L Wang, Y Lin, S Wang… - Journal of …, 2022 - Wiley Online Library
Cancer vaccines critically rely on the availability of targetable immunogenic cancer‐specific
neoepitopes. However, mutation‐based immunogenic neoantigens are rare or even non …

Harnessing stem cell-derived extracellular vesicles for the regeneration of degenerative bone conditions

Z Jia, S Zhang, W Li - International Journal of Nanomedicine, 2023 - Taylor & Francis
Degenerative bone disorders such as intervertebral disc degeneration (IVDD), osteoarthritis
(OA), and osteoporosis (OP) pose significant health challenges for aging populations and …

Engineering multifunctional dynamic hydrogel for biomedical and tissue regenerative applications

B Yin, M Gosecka, M Bodaghi, D Crespy… - Chemical Engineering …, 2024 - Elsevier
Hydrogels have emerged in various biomedical applications, including tissue engineering
and medical devices, due to their ability to imitate the natural extracellular matrix (ECM) of …

Exosome‐derived circTFDP2 promotes prostate cancer progression by preventing PARP1 from caspase‐3‐dependent cleavage

L Ding, Q Zheng, Y Lin, R Wang… - Clinical and …, 2023 - Wiley Online Library
Abstract Background Circular RNAs (circRNAs) have been reported to play a significant role
in tumorigenesis. However, the detailed function of circRNA in prostate cancer (PCa) is still …

Extracellular vesicles-loaded DNA hydrogels: a promising candidate for cartilage organoids engineering

Z Ma, Y Wu, G Li, J Liu, Z Geng, J Su - Chemical Engineering Journal, 2023 - Elsevier
Articular cartilage lesion such as osteoarthritis (OA) is becoming a serious threat to global
human health. In recent years, as a new paradigm in cartilage tissue engineering and …

[HTML][HTML] Harnessing exosomes as cutting-edge drug delivery systems for revolutionary osteoarthritis therapy

J Lu, Y Zhang, X Yang, H Zhao - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Exosomes, remarkable extracellular vesicles, have emerged as an advanced frontier in
intercellular communication. This remarkable capacity positions them as promising …