Recent developments in optical resolution

R Siedlecka - Tetrahedron, 2013 - Elsevier
Resolution methods of racemic or enriched mixtures are continuously exploited and
developed, particularly to obtain both enantiomers of chiral compounds. This compilation …

The way from isostructurality to polymorphism. Where are the borders? The role of supramolecular interactions and crystal symmetries

P Bombicz - Crystallography Reviews, 2017 - Taylor & Francis
To produce substances with required physico-chemical properties demands the recognition
of structural features of materials. It includes polymorphism and isostructurality which are …

Green and strategic approach for chiral resolution by diastereomeric salt formation: the study of racemic ibuprofen

HL Lee, YL Hung, A Amin, DE Pratama… - Industrial & Engineering …, 2023 - ACS Publications
As diastereomeric salt formation is the most popular method for the industrial preparation of
single enantiomers, this method is chosen to resolve enantiomers of ibuprofen (IBU) in the …

Nonsteroidal Anti-Inflammatory Drugs–1-Phenylethylamine Diastereomeric Salts: A Systematic Solid-State Investigation

P Rossi, J Ceccarelli, S Milazzo, P Paoli… - Crystal Growth & …, 2021 - ACS Publications
The solid-state investigation of the diastereomeric salts (S)-ibuprofen (S-Ibu),(S)-
naproxen,(S-Nap), and (S)-ketoprofen (S-Ket) with (R)-(+)-and (S)-(−)-1-phenylethylamine …

High-Pressure Crystallization and Structural Transformations in Compressed R,S-Ibuprofen

K Ostrowska, M Kropidłowska… - Crystal Growth & …, 2015 - ACS Publications
R, S-Ibuprofen dissolved in chiral and achiral solvents recrystallizes at varied pressure and
temperature in the same racemic form I of monoclinic space group P 21/c. At 4.0 GPa the …

Preparation of psebs membranes bearing (s)-(−)-methylbenzylamine as chiral selector

M Otmar, J Gaálová, J Žitka, L Brožová… - European Polymer …, 2020 - Elsevier
Nowadays, there is a strong need for replacement of racemates by enantiomerically pure
drugs. Enantioseparation on polymer membranes seems to be one of the promising and …

Structure Determination of Multicomponent Crystalline Phases of (S)-Ibuprofen and l-Proline from Powder X-ray Diffraction Data, Augmented by Complementary …

OA Rahal, PA Williams, CE Hughes… - Crystal Growth & …, 2021 - ACS Publications
Two multicomponent crystalline phases of (S)-ibuprofen and l-proline with 1: 1 stoichiometry
are reported, specifically a nonsolvate phase (Ibu-Pro) and a quarter-hydrate phase (Ibu-Pro …

Impact of a partial solid solution and water molecules on the formation of fibrous crystals and fluid inclusions

L Marc, C Lopes, JM Schneider, M Sanselme… - Crystals, 2021 - mdpi.com
Resolution of (±) ibuprofen using S-α-Methylbenzylamine in pure ethanol leads to the
enriched S-IBU/S-αMBA diastereomeric salt which crystallizes as very fine needles. In order …

Diastereomer salt formation of ibuprofen in supercritical carbon dioxide

G Bánsághi, E Székely, DM Sevillano, Z Juvancz… - The Journal of …, 2012 - Elsevier
The first in situ diastereomeric salt formation reaction in supercritical carbon dioxide is
reported in this paper. The reaction studied was the salt formation between racemic …

Synthesis, crystal structure and thermal investigation of molecular salts of (R)-1-phenylethanamine combined with quantum chemical studies

HR Rajegowda, BS Chethan, NK Lokanath… - Journal of Molecular …, 2023 - Elsevier
Abstract Molecular salts (R)-1-phenylethanaminium oxalate (1),(R)-1-phenylethanaminium 2-
carboxy-4, 6-dinitrophenolate (2) and (R)-1-phenylethanaminium 4-methylbenzenesulfonate …