Nearly all genetic variants that influence disease risk have human-specific origins; however,
the systems they influence have ancient roots that often trace back to evolutionary events …

First discovered by Friedenstein in 1976, mesenchymal stem cells (MSCs) are adult stem
cells found throughout the body that share a fixed set of characteristics. Discovered initially …

Bone has well documented natural healing capacity that normally is sufficient to repair
fractures and other common injuries. However, the properties of bone change throughout …

Mesenchymal stem cells (MSCs) are multipotent cells capable of self-renewal and
differentiation. There is increasing evidence of the therapeutic value of MSCs in various …

Introduction Administration of mesenchymal stem cells (MSCs) represents a promising
treatment option for patients suffering from immunological and degenerative disorders …

Mesenchymal stromal cells (MSCs) are currently being investigated for use in a wide variety
of clinical applications. For most of these applications, systemic delivery of the cells is …

Following their discovery over 50 years ago, mesenchymal stromal cells (MSCs) have
become one of the most studied cellular therapeutic products by both academia and industry …

Mesenchymal stromal cells (MSCs) are promising candidates for tissue engineering and
regenerative medicine. The multipotent stem cell component of MSC isolates is able to …

Mesenchymal stem cells (MSCs) are partially defined by their ability to differentiate into
tissues including bone, cartilage and adipose in vitro, but it is their trophic, paracrine and …

Introduction Different mesenchymal stromal cells (MSC) have been successfully isolated
and expanded in vitro and nowadays they are tested in clinical trials for a wide variety of …