Although recent years have witnessed significant advances in the development of catalytic,
enantioselective halofunctionalizations of alkenes, the related dihalogenation of olefins to …

During the last decade a number of powerful asymmetric reactions have emerged as a result
of the growing need to develop efficient and practical syntheses of biologically active …

The oxidation of a range of cyclic allylic alcohols and amides with OsO4/TMEDA is
presented. Under these conditions, hydrogen bonding control leads to the (contrasteric) …

Während in den letzten Jahren signifikante Fortschritte bei der Entwicklung katalytischer,
enantioselektiver Halogenfunktionalisierungen von Alkenen erzielt wurden, ist die …

Selective cis-dihydroxylation of olefins with the aid of a triple catalytic system using H2O2 as
the terminal oxidant has been developed. In this process Os (VI) is recycled to Os (VIII) by a …

A flexible route to polyhydroxylated pyrrolizidine alkaloids is described, starting from
commercially available N-Boc pyrrole and using a partial reduction as the key step. Tactics …

The ammonium-directed olefinic oxidation of a range of cyclic allylic and homoallylic amines
has been investigated. Functionalization of a range of allylic 3-(N, N-dibenzylamino) …

A general strategy for the production of pyrrolizidine alkaloids is described, starting from
intermediate (+)− 9. The key features are diastereoselective dihydroxylation, inversion at the …

A concise total synthesis of 1-epiaustraline 3 is described that utilizes a diastereoselective
Birch reduction of an electron-deficient pyrrole and a chelation-controlled vinyl Grignard …

The following account describes our work on the development and utilisation of the directed
dihydroxylation reaction. Our preliminary thoughts and experiments are described, as is the …