Otitis media and its consequences: beyond the earache

A Vergison, R Dagan, A Arguedas… - The Lancet infectious …, 2010 - thelancet.com
An international group of multidisciplinary experts on middle-ear and paediatric infections
met to explore where consensus exists on the management of acute otitis media. After …

Pneumococcal capsular polysaccharides conjugated to protein D for prevention of acute otitis media caused by both Streptococcus pneumoniae and non-typable …

R Prymula, P Peeters, V Chrobok, P Kriz, E Novakova… - The Lancet, 2006 - thelancet.com
Background Acute otitis media is one of the most commonly-diagnosed childhood infections.
This study assessed the efficacy of a novel vaccine that contained polysaccharides from 11 …

Epidemiology of acute otitis media in children of Latin America and the Caribbean: a systematic review and meta-analysis

A Bardach, A Ciapponi, S Garcia-Marti… - International journal of …, 2011 - Elsevier
BACKGROUND: Acute otitis media (AOM) is one of the most common childhood diseases
requiring antimicrobial prescription in pre-school children. This systematic review aimed to …

[HTML][HTML] The Pneumococcal Serine-Rich Repeat Protein Is an Intra-Species Bacterial Adhesin That Promotes Bacterial Aggregation In Vivo and in Biofilms

CJ Sanchez, P Shivshankar, K Stol… - PLoS …, 2010 - journals.plos.org
The Pneumococcal serine-rich repeat protein (PsrP) is a pathogenicity island encoded
adhesin that has been positively correlated with the ability of Streptococcus pneumoniae to …

[HTML][HTML] Acute otitis media, antimicrobial prescriptions, and medical expenses among children in the United States during 2011–2016

JA Suaya, BD Gessner, S Fung, S Vuocolo, J Scaife… - Vaccine, 2018 - Elsevier
Introduction We analyzed outpatient visits, incidence, antimicrobial prescriptions, and
medical expenditures for acute otitis media (AOM) in the United States during 2011–2016 …

Nasopharyngeal microbiota in infants with acute otitis media

M Hilty, W Qi, SD Brugger, L Frei… - Journal of infectious …, 2012 - academic.oup.com
Background. Interspecies interactions of the nasopharyngeal microbiota are likely to be
involved in the pathogenesis of acute otitis media (AOM). Capturing the breadth of microbial …

Acute otitis media in young children–what do parents say?

C Barber, S Ille, A Vergison, H Coates - International journal of pediatric …, 2014 - Elsevier
Abstract Objectives The Ear infections Attitudes Research study investigated parental
attitudes and awareness towards acute otitis media (AOM) and evaluated the burden of …

Otitis media across nine countries: disease burden and management

A Arguedas, K Kvaerner, J Liese, AGM Schilder… - International journal of …, 2010 - Elsevier
OBJECTIVE: To assess the perceived disease burden and management of otitis media (OM)
among an international cohort of experienced physicians. METHODS: A cross-sectional …

Influenza-induced inflammation drives pneumococcal otitis media

KR Short, PC Reading, LE Brown… - Infection and …, 2013 - Am Soc Microbiol
Influenza A virus (IAV) predisposes individuals to secondary infections with the bacterium
Streptococcus pneumoniae (the pneumococcus). Infections may manifest as pneumonia …

Antibodies mediate formation of neutrophil extracellular traps in the middle ear and facilitate secondary pneumococcal otitis media

KR Short, M von Köckritz-Blickwede… - Infection and …, 2014 - Am Soc Microbiol
Otitis media (OM)(a middle ear infection) is a common childhood illness that can leave some
children with permanent hearing loss. OM can arise following infection with a variety of …