Coumarin heterocyclic derivatives: chemical synthesis and biological activity

FG Medina, JG Marrero, M Macías-Alonso… - Natural product …, 2015 - pubs.rsc.org
Coumarin heterocyclic derivatives: chemical synthesis and biological activity - Natural Product
Reports (RSC Publishing) DOI:10.1039/C4NP00162A Royal Society of Chemistry View PDF …

Metal-free multicomponent syntheses of pyridines

C Allais, JM Grassot, J Rodriguez… - Chemical …, 2014 - ACS Publications
They react according to a succession of mono-or bimolecular processes to form at the end
one product that incorporates important portions and functionalities of the starting materials …

A review: Biologically active 3, 4-heterocycle-fused coumarins

F Salehian, H Nadri, L Jalili-Baleh… - European Journal of …, 2021 - Elsevier
The combination of heterocycles offers a new opportunity to create novel multicyclic
compounds having improved biological activity. Coumarins are ubiquitous natural …

Synthesis of polyheterocycles via multicomponent reactions

IA Ibarra, A Islas-Jácome… - Organic & Biomolecular …, 2018 - pubs.rsc.org
Polyheterocycles are one of the most desired synthetic targets due to their numerous and
valuable applications in various fields. Multicomponent reactions (MCRs) are highly …

A decade update on solvent and catalyst-free neat organic reactions: a step forward towards sustainability

A Sarkar, S Santra, SK Kundu, A Hajra, GV Zyryanov… - Green …, 2016 - pubs.rsc.org
Particular success has been achieved in the synthesis of new products and in processes
since the twelve principles of “green chemistry” were formulated in the 1990s. These …

Oxadiazole: A highly versatile scaffold in drug discovery

N Desai, J Monapara, A Jethawa… - Archiv der …, 2022 - Wiley Online Library
As a pharmacologically important heterocycle, oxadiazole paved the way to combat the
problem associated with the confluence of many commercially available drugs with different …

Synthesis, biological evaluation and molecular docking study of some novel indole and pyridine based 1, 3, 4-oxadiazole derivatives as potential antitubercular …

NC Desai, H Somani, A Trivedi, K Bhatt… - Bioorganic & medicinal …, 2016 - Elsevier
A series of indole and pyridine based 1, 3, 4-oxadiazole derivatives 5a–t were synthesized
and evaluated for their in vitro antitubercular activity against Mycobacterium tuberculosis H …

An overview on the synthesis of fused pyridocoumarins with biological interest

MD Douka, KE Litinas - Molecules, 2022 - mdpi.com
Pyridocoumarins are a class of synthetic and naturally occurring organic compounds with
interesting biological activities. This review focuses on the synthetic strategies for the …

5-Aminopyrazole as precursor in design and synthesis of fused pyrazoloazines

R Aggarwal, S Kumar - Beilstein Journal of Organic Chemistry, 2018 - beilstein-journals.org
The condensation of 5-aminopyrazole with various bielectrophilic moieties results in the
formation of pyrazoloazines, an interesting array of fused heterocyclic systems. The …

Aminoazole-based diversity-oriented synthesis of heterocycles

MV Murlykina, AD Morozova, IM Zviagin… - Frontiers in …, 2018 - frontiersin.org
The comprehensive review contains the analysis of literature data concerning reactions of
heterocyclization of aminoazoles and demonstrates the application of these types of …