Nitroxides, also known as nitroxyl radicals, are long-lived or stable radicals with the general
structure R1R2N–O•. The spin distribution over the nitroxide N and O atoms contributes to …

This Perspective illustrates the defining characteristics of free radical chemistry, beginning
with its rich and storied history. Studies from our laboratory are discussed along with recent …

The rapid generation of molecular complexity from simple starting materials is of paramount
importance in synthetic chemistry. The unique combination of high reactivity and high …

The organic nitroxyl radical, TEMPO (2, 2, 6, 6-tetramethylpiperidine-N-oxyl), finds a variety
of industrial applications for chemical transformations. Because of economic and …

Covering: 1964 to 2013 Natural products from bacteria and plants have played a leading
role in cancer drug discovery resulting in a large number of clinically useful agents. In …

The ability to procure useful quantities of a molecule by simple, scalable routes is emerging
as an important goal in natural product synthesis. Approaches to molecules that yield …

Diels–Alder (D–A) reaction is undoubtedly the most powerful [4+ 2] cycloaddition reaction in
organic synthesis. It has been always considered as a model and a symbol of cycloaddition …

Neurodegenerative diseases and spinal cord injury affect approximately 50 million people
worldwide, bringing the total healthcare cost to over 600 billion dollars per year. Nervous …

Tetramic acid (pyrrolidine-2, 4-dione) compounds, isolated from a variety of marine and
terrestrial organisms, have attracted considerable attention for their diverse, challenging …

The dimeric lindenane sesquiterpenoids are mainly isolated from the plants of
Chloranthaceae family. Structurally, they have a crowded molecular scaffold decorated with …