Skin aging, cellular senescence and natural polyphenols

E Csekes, L Račková - International journal of molecular sciences, 2021 - mdpi.com
The skin, being the barrier organ of the body, is constitutively exposed to various stimuli
impacting its morphology and function. Senescent cells have been found to accumulate with …

[HTML][HTML] ACE2, TMPRSS2 distribution and extrapulmonary organ injury in patients with COVID-19

M Dong, J Zhang, X Ma, J Tan, L Chen, S Liu… - Biomedicine & …, 2020 - Elsevier
At the end of 2019, the coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in China. Currently, it is …

Therapeutic blockade of inflammation in severe COVID-19 infection with intravenous N-acetylcysteine

H Ibrahim, A Perl, D Smith, T Lewis, Z Kon… - Clinical …, 2020 - Elsevier
Abstract Glucose 6-phosphate dehydrogenase (G6PD) deficiency facilitates human
coronavirus infection due to glutathione depletion. G6PD deficiency may especially …

Cancer associates with risk and severe events of COVID‐19: A systematic review and meta‐analysis

Y Tian, X Qiu, C Wang, J Zhao, X Jiang… - … journal of cancer, 2021 - Wiley Online Library
Evidence is mounting to indicate that cancer patients may have more likelihood of having
coronavirus disease 2019 (COVID‐19) but lack consistency. A robust estimate is urgently …

[HTML][HTML] Effects of cancer on patients with COVID-19: a systematic review and meta-analysis of 63,019 participants

L Yang, P Chai, J Yu, X Fan - Cancer Biology & Medicine, 2021 - ncbi.nlm.nih.gov
Objective: Patients with underlying diseases are more vulnerable to coronavirus disease
2019 (COVID-19). The purpose of this study was to investigate cancer incidence in patients …

ACE2 in the era of SARS-CoV-2: controversies and novel perspectives

F Saponaro, G Rutigliano, S Sestito… - Frontiers in Molecular …, 2020 - frontiersin.org
Angiotensin-converting enzyme 2 (ACE2) is related to ACE but turned out to counteract
several pathophysiological actions of ACE. ACE2 exerts antihypertensive and …

The epigenetic implication in coronavirus infection and therapy

S Atlante, A Mongelli, V Barbi, F Martelli, A Farsetti… - Clinical …, 2020 - Springer
Epigenetics is a relatively new field of science that studies the genetic and non-genetic
aspects related to heritable phenotypic changes, frequently caused by environmental and …

Thymoquinone: A promising natural compound with potential benefits for COVID-19 prevention and cure

OA Badary, MS Hamza, R Tikamdas - Drug design, development …, 2021 - Taylor & Francis
COVID-19 has caused a major global health crisis, as excessive inflammation, oxidation,
and exaggerated immune response in some sufferers can lead to a condition known as …

[HTML][HTML] Endothelial cells and SARS-CoV-2: An intimate relationship

LC Barbosa, TL Goncalves, LP de Araujo… - Vascular …, 2021 - Elsevier
Abstract Angiotensin-converting enzyme 2 (ACE2) is an important player of the renin-
angiotensin-aldosterone system (RAAS) in regulating the conversion of angiotensin II into …

Increased expression of ACE2, the SARS-CoV-2 entry receptor, in alveolar and bronchial epithelium of smokers and COPD subjects

M Jacobs, HP Van Eeckhoutte… - European …, 2020 - Eur Respiratory Soc
Angiotensin-converting enzyme 2 (ACE2) has been identified as the cell entry receptor used
by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)[1, 2]. Importantly …