Tumor microenvironment: A playground for cells from multiple diverse origins

D Bharadwaj, M Mandal - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
Tumor microenvironment is formed by various cellular and non-cellular components which
interact with one another and form a complex network of interactions. Some of these cellular …

Advances in liposome-based delivery of RNA therapeutics for cancer treatment

M Sanati, AR Afshari, SS Ahmadi, P Kesharwani… - Progress in Molecular …, 2024 - Elsevier
Liposomal drug delivery systems stand as versatile therapeutic platforms for precisely
targeting related elements in cancerous tissues owing to their intrinsic passive and acquired …

[HTML][HTML] Regulatory Insights into Nanomedicine and Gene Vaccine Innovation: Safety Assessment, Challenges, and Regulatory Perspectives

EB Souto, C Blanco-Llamero, K Krambeck, NS Kiran… - Acta Biomaterialia, 2024 - Elsevier
This analysis explores the principal regulatory concerns linked to nanomedicines and gene
vaccines, including the complexities involved and the perspectives on how to navigate them …

[PDF][PDF] Recent Findings on Therapeutic Cancer Vaccines: An Updated Review

S Sheikhlary - 2024 - videleaf.com
Cancer remains one of the global leading causes of death and various vaccines have been
developed over the years against it, including cell-based, nucleic acid-based, and viral …

[HTML][HTML] Design of a targeted dual drug delivery system for boosting the efficacy of photoimmunotherapy against melanoma proliferation and metastasis

Y Chen, S Xu, S Ren, J Zhang, J Xu, Y Song… - Journal of Advanced …, 2024 - Elsevier
Introduction The combination of a photosensitizer and indoleamine-2, 3 dioxygenase (IDO)
inhibitor provides a promising photoimmunotherapy (PIT) strategy for melanoma treatment …

Chemo-immunotherapy by nanoliposomal epacadostat and docetaxel combination to IDO1 inhibition and tumor microenvironment suppression

R Khoshkhabar, M Yazdani, SH Alavizadeh… - International …, 2024 - Elsevier
The over-activation of tryptophan (Trp) metabolism to kynurenine (Kyn) catalyzed by
Indoleamine 2, 3-dioxygenase-1 (IDO1) enzyme, is one of the main metabolic pathways …

Novel Therapeutic Applications of Nanoparticles and Bio-nanocomposites in Modern Biomedicine

S Aminnezhad, TA Faraj, NH Hama, M Alavi… - … Nanomaterials and their …, 2024 - Springer
Nanoparticles play a crucial role in modern medicine, spanning diagnostics, treatment
modalities, and drug delivery systems. Their significance lies in revolutionizing healthcare …