Gangliosides are highly abundant in the human brain where they are involved in major
biological events. In brain cancers, alterations of ganglioside pattern occur, some of which …

Background Recent evidences have suggested the involvement of toll-like receptor (TLR)-4
in the pathogenesis of cerebral cavernous malformations (CCM). Elevated frequency of …

Cerebral cavernous malformations (CCMs) are angiographically occult vascular lesions that
present with a variety of neurological symptoms, including seizures, features of raised …

The neuropathology of epilepsy aims at diagnosing the cerebral lesions underlying epilepsy
that are obtained from epilepsy surgery, or rarely from biopsy or autopsy. The main …

Cerebral cavernous malformation (CCM) is a vascular lesion of the central nervous system
that may lead to distinct symptoms among patients including cerebral hemorrhages …

BACKGROUND Cerebral cavernous malformations (CCMs) are microvascular CNS lesions
prone to hemorrhage leading to neurological sequela such as stroke and seizure. A subset …

A large body of evidence has suggested that the natural biology for symptomatic cerebral
cavernous malformations (CCMs) is dynamic. These lesions exhibit a temporal clustering …

Background Familial forms of cavernous malformations (CMs) often occur as multiple
lesions. Nevertheless, the presence of a single CM does not exclude the familiarity. The aim …

Nuclear accumulation of the small phosphoprotein integrin cytoplasmic domain–associated
protein-1 (ICAP1) results in recruitment of its binding partner, Krev/Rap1 interaction trapped …

Neuropathological examination of the temporal lobe provides a better understanding and
management of a wide spectrum of diseases. We focused on inflammatory diseases …