Angiogenesis or formation of new blood vessels from preexisting vasculature is a key
process in some physiological conditions such as wound healing, growth, and action of …

Diabetes mellitus (DM) is a chronic metabolic disease characterized by the presence of
hyperglycemia, which can lead to many complications over time. These complications, such …

Diabetes mellitus increases the risk of developing heart failure, and the co-existence of both
diseases worsens cardiovascular outcomes, hospitalization, and the progression of heart …

Type 2 diabetes mellitus is a complex disease and a chronic health-care problem.
Nowadays, because of alteration of lifestyle such as lack of exercise, intake of high fat diet …

Background Recent evidence indicates that inhibition of histone deacetylase (HDAC)
protects the heart against myocardial injury and stimulates endogenous angiomyogenesis …

Obesity is recognized as a chronic low grade and systemic inflammatory disease.
Angiogenesis is critical for adipose tissue expansion. Several evidences have demonstrated …

Background Diabetes is a complex metabolic disease characterized by hyperglycemia,
plaguing the whole world. However, the action mode of multi-component and multi-target for …

Glutaredoxin-1 (Glrx) is a cytosolic enzyme that regulates diverse cellular function by
removal of GSH adducts from S-glutathionylated proteins including signaling molecules and …

The balance of pro-angiogenic and anti-angiogenic factors has a significant role in the
development of diabetic cardiomyopathy. The purpose of this study was to examine the …

Background: Diabetes mellitus (DM) is one of the major risk factors for cardiovascular
disease, leading to endothelial dysfunction and angiogenesis impairment. MiR-126 and miR …