Vitamin C (VitC) is an essential vitamin that needs to be provided through exogenous
sources. It is a potent anti-oxidant, and an essential cofactor for many enzymes including a …

Inorganic arsenic (iAs) causes cancer by initiating dynamic transitions between epithelial
and mesenchymal cell phenotypes. These transitions transform normal cells into cancerous …

Human γδ T cells are potent cytotoxic effector cells, produce a variety of cytokines, and can
acquire regulatory activity. Induction of FOXP3, the key transcription factor of regulatory T …

Epigenetics has emerged as one of the fastest growing concepts, adding more than 45 new
publications every day, spreading through various fields (1). Conrad Waddington coined the …

Immune cells are part of the most dynamic organ system in the body, which fights primarily
against infections and maintains cellular integrity and homeostasis. Memory is a unique …

Abstract γδ T cells express unique T cell receptor (TCR) γ and TCR δ chains, with structural
and functional heterogeneity. Taking advantage of the diverse γδ TCR repertoire or other …

Epigenetics refers to heritable phenotype changes that do not involve alterations in the DNA
sequence. While DNA methylation and histone modifications represent the classical …

Non-infectious uveitis is a clinically heterogenous disease, which can cause chronic
relapsing and remitting chorioretinal inflammation and vision loss. The disease is incurable …