Ascorbic acid (AA), also known as vitamin C, was initially identified as the factor preventing
the scurvy disease, and became very popular for its antioxidant properties. It is an important …

Chronic obstructive pulmonary disease (COPD) is one of the most common chronic illnesses
in the world. The disease encompasses emphysema, chronic bronchitis, and small airway …

Intravenous administration of vitamin C has been shown to decrease oxidative stress and, in
some instances, improve physiological function in adult humans. Oral vitamin C …

Capsaicin (CAP) activates the transient receptor potential vanilloid 1 (TRPV1) channel on
sensory neurons, improving ATP production, vascular function, fatigue resistance, and thus …

Purpose It has been suggested that part of the failure of antioxidant supplementation to
reduce oxidative stress and promote health is that it has been administered in humans with …

Recent research highlights the importance of redox signalling pathway activation by
contraction-induced reactive oxygen species (ROS) and nitric oxide (NO) in normal exercise …

Nutritional abnormalities are frequent in different chronic respiratory diseases such as
chronic obstructive pulmonary disease (COPD), bronchiectasis, cystic fibrosis (CF) …

Background Differentiating asthma from other causes of chronic airflow limitation, such as
chronic obstructive pulmonary disease (COPD), can be difficult in a typical outpatient setting …

Methods Reports in the peer-reviewed literature were analyzed and published findings
integrated to synthesize an overview of ROS as agents of fatigue. Results Muscle tissue …

Background In the early literature, unintentional vitamin C deficiency in humans was
associated with heart failure. Experimental vitamin C deficiency in guinea pigs caused …