Inflammatory bowel disease (IBD) comprises a group of chronic inflammatory disorders of
the gastrointestinal tract. Accumulating evidence shows that the development of IBD is …

The gastrointestinal (GI) system contains many different types of immune cells, making it a
key immune organ system in the human body. In the last decade, our knowledge has …

Psoriasis is a chronic inflammatory skin disease characterized by accelerated tumor
necrosis factor-α/interleukin-23/interleukin-17 axis, hyperproliferation and abnormal …

Short-chain fatty acids (SCFAs) are the main metabolites produced by the bacterial
fermentation of dietary fiber, and they play a critical role in the maintenance of intestinal …

Studies in recent years have identified a pivotal role of the cytokine IL-23 in the
pathogenesis of inflammatory bowel diseases (IBD: Crohn´ s disease, ulcerative colitis) and …

Incorporation of microbiome data has recently become important for prevention, diagnosis,
and treatment of colorectal cancer, and several species of bacteria were shown to be …

Worldwide,∼ 196 million are afflicted with endometriosis, a painful disease in which
endometrial tissue implants and proliferates on abdominal peritoneal surfaces. Theories on …

The gastrointestinal (GI) tract is a highly complex organ composed of the intestinal
epithelium layer, intestinal microbiota, and local immune system. Intestinal microbiota …

Lactobacillus reuteri (L. reuteri) has been recognized as a probiotic to improve liver health,
whereas the mechanism behind is still unknown. Herein, mice were gavaged with a strain of …

Group 3 innate lymphoid cells (ILC3s) are crucial for the maintenance of host–microbiota
homeostasis in gastrointestinal mucosal tissues. The mechanisms that maintain lineage …