Abnormal choline metabolism is emerging as a metabolic hallmark that is associated with
oncogenesis and tumour progression. Following transformation, the modulation of enzymes …

This review presents the current state of the art regarding multiparametric magnetic
resonance (MR) imaging of prostate cancer. Technical requirements and clinical indications …

The field of prostate cancer has been the subject of extensive research that has resulted in
important discoveries and shaped our appreciation of this disease and its management …

All cancers tested so far display abnormal choline and ethanolamine phospholipid
metabolism, which has been detected with numerous magnetic resonance spectroscopy …

Metabolic profiling, metabolomic and metabonomic studies require robust study protocols for
any large-scale comparisons and evaluations. Detailed methods for solution-state NMR …

Background The genetic and molecular mechanisms responsible for and associated
specifically with the development and progression of malignant prostate cells are largely …

Anabolic metabolism mediated by aberrant growth factor signalling fuels tumour growth and
progression. The first biochemical descriptions of the altered metabolic nature of solid …

Magnetic resonance (MR) examinations of men with prostate cancer are most commonly
performed for detecting, characterizing, and staging the extent of disease to best determine …

Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …

Purpose To evaluate the clinical value of diffusion‐weighted imaging (DWI) and dynamic
MRI in combination with T2‐weighted imaging (T2W) for the detection of prostate cancer …