[HTML][HTML] Proteomic developments in the analysis of formalin-fixed tissue

OJR Gustafsson, G Arentz, P Hoffmann - Biochimica et Biophysica Acta …, 2015 - Elsevier
Retrospective proteomic studies, including those which aim to elucidate the molecular
mechanisms driving cancer, require the assembly and characterization of substantial patient …

Quantitative proteomics in lung cancer

CHY Cheung, HF Juan - Journal of biomedical science, 2017 - Springer
Lung cancer is the most common cause of cancer-related death worldwide, less than 7% of
patients survive 10 years following diagnosis across all stages of lung cancer. Late stage of …

Liquid trap or separator for electrosurgical applications

T Karancsi, L Godorhazy, D Szalay, Z Takats… - US Patent …, 2021 - Google Patents
An apparatus for mass spectrometry and/or ion mobility spectrometry is disclosed
comprising a first device arranged and adapted to generate aerosol, smoke or vapor from a …

Proteomic biomarkers of non-small cell lung cancer patients

K Baran, E Brzeziańska-Lasota - Advances in Respiratory …, 2021 - journals.viamedica.pl
Lung cancer is a disease with a very low 5-year survival rate (6–13%) worldwide. The most
frequently diagnosed histological type of this cancer is non-small cell lung cancer (NSCLC) …

Identification and characterization of potential biomarkers by quantitative tissue proteomics of primary lung adenocarcinoma

CH Hsu, CW Hsu, C Hsueh, CL Wang, YC Wu… - Molecular & cellular …, 2016 - ASBMB
Lung cancer is the leading cause of cancer-related death worldwide. Both diagnostic and
prognostic biomarkers are urgently needed to increase patient survival. In this study, we …

Interleukin-11: a potential biomarker and molecular therapeutic target in non-small cell lung cancer

JH Leung, B Ng, WW Lim - Cells, 2022 - mdpi.com
Non-small cell lung cancer (NSCLC) accounts for 85% of lung cancer and is a fast
progressive disease when left untreated. Identification of potential biomarkers in NSCLC is …

Sialic acid linkage-specific quantitative N-glycoproteomics using selective alkylamidation and multiplex TMT-labeling

H Yang, Z Tian - Analytica Chimica Acta, 2022 - Elsevier
Protein sialylation participates many biological processes in a linkage-specific manner, and
aberrant sialylation has been associated with many malignant diseases. Mass spectrometry …

Recent mass spectrometry-based proteomics for biomarker discovery in lung cancer, COPD, and asthma

K Fujii, H Nakamura, T Nishimura - Expert Review of Proteomics, 2017 - Taylor & Francis
Introduction: Lung cancer and related diseases have been one of the most common causes
of deaths worldwide. Genomic-based biomarkers may hardly reflect the underlying dynamic …

Proteomic analyses identify HK1 and ATP5A to be overexpressed in distant metastases of lung adenocarcinomas compared to matched primary tumors

H Pasternack, M Polzer, T Gemoll, C Kümpers… - Scientific Reports, 2023 - nature.com
Lung cancer is the leading cause of cancer-related deaths worldwide with lung
adenocarcinoma (LUAD) being the most common type. Genomic studies of LUAD have …

In vivo imaging of the Muc5b gel-forming mucin

C Portal, V Gouyer, M Magnien, S Plet, F Gottrand… - Scientific Reports, 2017 - nature.com
Gel-forming mucins are macromolecules produced by goblet cells and responsible for the
mucus gel formation. Changes in goblet cell density and in gel-forming mucin production …