The complex microenvironment in which malignant tumor cells grow is crucial for cancer
progression. The physical and biochemical characteristics of this niche are involved in …

Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

This review provides a detailed overview of the rapidly advancing field of biofabrication,
particularly with regards to the use of photo-cross-linking (ie, light-based) techniques. The …

Tissue engineering has produced innovative tools for cancer research. 3D cancer models
based on molecularly designed biomaterials aim to harness the dimensionality and …

Cancer is a multifaceted pathology, where cellular and acellular players interact to drive
cancer progression and, in the worst-case, metastasis. The current methods to investigate …

Abstract 3D bioprinting is emerging as a promising technology for fabricating complex tissue
constructs with tailored biological components and mechanical properties. Recent advances …

Hyaluronic acid (HA) is an attractive anionic polysaccharide polymer with inherent
pharmacological properties and versatile chemical groups for modification. Due to their …

Metastasis is the spread of cancer cells from a primary tumor to distant sites within the body
to establish secondary tumors. Although this is an inefficient process, the consequences are …

The mechanisms behind cancer initiation and progression are not clear. Therefore,
development of clinically relevant models to study cancer biology and drug response in …

Tumor initiation and progression are somatic evolutionary processes driven by the
accumulation of genetic alterations, some of which confer selective fitness advantages to the …