The kainic acid model of temporal lobe epilepsy has greatly contributed to the
understanding of the molecular, cellular and pharmacological mechanisms underlying …

Astroglial networks constitute a non-neuronal communication system in the brain and are
acknowledged modulators of synaptic plasticity. A sophisticated set of transmitter receptors …

Excitatory and inhibitory (EI) interactions shape network activity. However, little is known
about the EI interactions in pathological conditions such as epilepsy. To investigate EI …

Precisely timed and dynamically balanced excitatory (E) and inhibitory (I) conductances
underlie the basis of neural network activity. Normal E/I balance is often shifted in epilepsy …

(1) Background: Ultrasound has been used for noninvasive stimulation and is a promising
technique for treating neurological diseases. Epilepsy is a common neurological disorder …

Methylenedioxymethamphetamine (MDMA; Ecstasy) is a popular drug of abuse with well-
documented acute effects on serotonergic, dopaminergic, and cholinergic transmitter …

Glutamate excitotoxicity accompanies numerous brain pathologies, including traumatic brain
injury, ischemic stroke, and epilepsy. Disturbances of the ion homeostasis, mitochondria …

The specific connectivity among principal cells and interneurons determines the flow of
activity in neuronal networks. To elucidate the connections between hippocampal principal …

Epilepsy is common brain dysfunction, where abnormal synchronized activities can be
observed across multiple brain regions. Low-frequency focused pulsed ultrasound has been …

Status epilepticus (SE) is associated with complex reorganization of hippocampal circuits
involving a significant loss of specific subtypes of GABAergic interneurons. While adaptive …