Animal experimentation in the Parkinson's disease (PD) field is a classic example of how the
use of animal models to study diseases can have a significant impact on human health …

Animal models are an important aid in experimental medical science because they enable
one to study the pathogenetic mechanisms and the therapeutic principles of treating the …

Parkinson's disease (PD) is a complex, multisystem disorder characterised by α-synuclein
(SNCA) pathology, degeneration of nigrostriatal dopaminergic neurons, multifactorial …

Although the cardinal manifestations of Parkinson's disease (PD) are attributed to a decline
in dopamine levels in the striatum, a breadth of non-motor features and treatment-related …

Neuropsychiatric symptoms seen in Alzheimer's disease (AD) are not simply a consequence
of neurodegeneration, but probably result from differential neurotransmitter alterations …

This paper provides an overview of the compensatory mechanisms which come into action
during experimental and human parkinsonism. The intrinsic properties of the dopaminergic …

We describe an enhancer trap transgenic zebrafish line, ETvmat2: GFP, in which most
monoaminergic neurons are labeled by green fluorescent protein (GFP) during embryonic …

An appreciation of the multiple roles that serotonin (5‐HT) may play in Parkinson's disease
(PD) has increased in recent years. Early pathological studies in PD demonstrated …

Major depression is a mental disorder often preceded by exposure to chronic stress or
stressful life events. Recently, animal models based on social conflict such as chronic social …

Non-human primate (NHP) models of Parkinson's disease (PD) have been essential in
understanding the pathophysiology and neural mechanisms underlying PD. The most …