Endogenous opiates and behavior: 2022

RJ Bodnar - Peptides, 2023 - Elsevier
This paper is the forty-fifth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Dynorphin 1-17 biotransformation peptides: properties, challenges and solutions for future therapeutics development

R Ballouze, SM Salhimi, N Mohtar… - Future Medicinal …, 2023 - Taylor & Francis
It is well established that endogenously produced dynorphin 1-17 (DYN 1-17) is susceptible
to enzymatic degradation, producing a variety of unique fragments in different tissue …

[HTML][HTML] Interleukin-4 mitigates anxiety-like behavior and loss of neurons and fiber tracts in limbic structures in a microglial PPARγ-dependent manner after traumatic …

H Pu, Y Wang, T Yang, RK Leak, RA Stetler, F Yu… - Neurobiology of …, 2023 - Elsevier
Traumatic brain injury (TBI) is commonly followed by intractable psychiatric disorders and
long-term changes in affect, such as anxiety. The present study sought to investigate the …

Peptide discovery across the spectrum of neuroinflammation; microglia and astrocyte phenotypical targeting, mediation, and mechanistic understanding

BA Benita, KM Koss - Frontiers in Molecular Neuroscience, 2024 - frontiersin.org
Uncontrolled and chronic inflammatory states in the Central Nervous System (CNS) are the
hallmark of neurodegenerative pathology and every injury or stroke-related insult. The key …

Dysregulation of kappa opioid receptor neuromodulation of lateral habenula synaptic function following a repetitive mild traumatic brain injury

WJ Flerlage, SC Simmons, EH Thomas, S Gouty… - Pharmacology …, 2024 - Elsevier
Mild traumatic brain injury (mTBI) increases the risk of affective disorders, anxiety and
substance use disorder. The lateral habenula (LHb) plays an important role in …

Detection of dynorphin 1-17 biotransformation fragments in human nasal polyps by UPLC-QTOF-MS

R Ballouze, MN Ismail, NS Abu Kassim… - Analytical and …, 2024 - Springer
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent inflammation of the
sinonasal mucosa. CRSwNP treatments are associated with inconsistent efficacy and …

[PDF][PDF] Analysis of genetic data to unravel the evolutionary history of hypothalamus neuropeptides and their role in cognition and behavior

M Sherafatizangeneh - 2023 - duo.uio.no
The hypothalamus is a small but powerful part of the brain that controls many vital bodily
functions. Its neurons and hormonal signaling network regulate body temperature, hunger …