The role of natural killer cells in autoimmune diseases

UC Kucuksezer, E Aktas Cetin, F Esen… - Frontiers in …, 2021 - frontiersin.org
Natural killer (NK) cells, the large granular lymphocytes differentiated from the common
lymphoid progenitors, were discovered in early 1970's. They are members of innate …

Risk factors, clinical features and treatment of Behçet's disease uveitis

Z Zhong, G Su, P Yang - Progress in Retinal and Eye Research, 2023 - Elsevier
Behçet's disease is a systemic vasculitis frequently associated with intraocular inflammation.
Recent findings identified independent clinical clusters in Behçet's disease, each involving …

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

Groupe Française d'Etude Génétique des … - Nature …, 2013 - nature.com
Ankylosing spondylitis is a common, highly heritable inflammatory arthritis affecting primarily
the spine and pelvis. In addition to HLA-B* 27 alleles, 12 loci have previously been identified …

Behcet's disease: A comprehensive review with a focus on epidemiology, etiology and clinical features, and management of mucocutaneous lesions

E Alpsoy - The Journal of dermatology, 2016 - Wiley Online Library
Behçet's disease (BD) is a chronic, relapsing, inflammatory multisystem disease of unknown
etiology. Oral ulcers, genital ulcers, cutaneous lesions, and ocular and articular involvement …

Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1

Y Kirino, G Bertsias, Y Ishigatsubo, N Mizuki… - Nature …, 2013 - nature.com
Individuals with Behçet's disease suffer from episodic inflammation often affecting the
orogenital mucosa, skin and eyes. To discover new susceptibility loci for Behçet's disease …

Behçet's disease: an overview of etiopathogenesis

P Leccese, E Alpsoy - Frontiers in immunology, 2019 - frontiersin.org
Behçet's disease (BD) is a systemic inflammatory disease with a chronic, relapsing-remitting
course of unknown etiology hallmarked predominantly by mucocutaneous lesions and …

[HTML][HTML] The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings

DA Martin, JE Towne, G Kricorian, P Klekotka… - Journal of Investigative …, 2013 - Elsevier
Although the histological changes seen in psoriasis have long been well characterized, the
underlying cellular and molecular mechanisms have only begun to be elucidated over the …

New IBD genetics: common pathways with other diseases

CW Lees, JC Barrett, M Parkes, J Satsangi - Gut, 2011 - gut.bmj.com
Complex disease genetics has been revolutionised in recent years by the advent of genome-
wide association (GWA) studies. The chronic inflammatory bowel diseases (IBDs), Crohn's …

Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease

EF Remmers, F Cosan, Y Kirino, MJ Ombrello… - Nature …, 2010 - nature.com
Behçet's disease is a genetically complex disease of unknown etiology characterized by
recurrent inflammatory attacks affecting the orogenital mucosa, eyes and skin. We performed …

Recent insights into the genetics of inflammatory bowel disease

JH Cho, SR Brant - Gastroenterology, 2011 - Elsevier
Inflammatory bowel diseases (IBDs) are complex, multifactorial disorders that comprise
Crohn's disease (CD) and ulcerative colitis (UC). Genome-wide association studies have …