Mitochondria play a pivotal role in bioenergetics and respiratory functions, which are
essential for the numerous biochemical processes underpinning cell viability. Mitochondrial …

Mitochondria are vital organelles with distinct morphological features and functional
properties. The dynamic network of mitochondria undergoes structural and functional …

Synaptic activity imposes large energy demands that are met by local adenosine
triphosphate (ATP) synthesis through glycolysis and mitochondrial oxidative …

Mitochondria are key determinants of cellular health. However, the functional role of
mitochondria varies from cell to cell depending on the relative demands for energy …

Mitochondrial transport along microtubules is mediated by Miro1 and TRAK adaptors that
recruit kinesin-1 and dynein-dynactin. To understand how these opposing motors are …

Mitochondria have a number of essential roles in neuronal function. Their complex mobility
patterns within neurons are characterized by frequent changes in direction. Mobile …

In the current model of mitochondrial trafficking, Miro1 and Miro2 Rho‐GTP ases regulate
mitochondrial transport along microtubules by linking mitochondria to kinesin and dynein …

Mitochondrial morphology is determined by a dynamic equilibrium between organelle fusion
and fission, but the significance of these processes in vertebrates is unknown. The …

Vigorous transport of cytoplasmic components along axons over substantial distances is
crucial for the maintenance of neuron structure and function. The transport of mitochondria …

Mitochondria are the primary energy-generating system in most eukaryotic cells.
Additionally, they participate in intermediary metabolism, calcium signaling, and apoptosis …