Molecular mechanism of interaction between SARS-CoV-2 and host cells and interventional therapy
Q Zhang, R Xiang, S Huo, Y Zhou, S Jiang… - Signal transduction and …, 2021 - nature.com
The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …
Cell entry by SARS-CoV-2
Severe acute respiratory syndrome virus 2 (SARS-CoV-2) invades host cells by interacting
with receptors/coreceptors, as well as with other cofactors, via its spike (S) protein that …
with receptors/coreceptors, as well as with other cofactors, via its spike (S) protein that …
Neuropilin-1 is a host factor for SARS-CoV-2 infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease 2019 (COVID-19), uses the viral spike (S) protein for host cell …
coronavirus disease 2019 (COVID-19), uses the viral spike (S) protein for host cell …
Mechanisms and regulation of endothelial VEGF receptor signalling
M Simons, E Gordon, L Claesson-Welsh - Nature reviews Molecular …, 2016 - nature.com
Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are uniquely
required to balance the formation of new blood vessels with the maintenance and …
required to balance the formation of new blood vessels with the maintenance and …
Molecular pharmacology of VEGF-A isoforms: binding and signalling at VEGFR2
Vascular endothelial growth factor-A (VEGF-A) is a key mediator of angiogenesis, signalling
via the class IV tyrosine kinase receptor family of VEGF Receptors (VEGFRs). Although …
via the class IV tyrosine kinase receptor family of VEGF Receptors (VEGFRs). Although …
SARS-CoV-2 spike protein co-opts VEGF-A/neuropilin-1 receptor signaling to induce analgesia
SARS-CoV-2 spike protein co-opts VEGF-A/neuropilin-1 recepto... : PAIN SARS-CoV-2 spike
protein co-opts VEGF-A/neuropilin-1 receptor signaling to induce analgesia : PAIN …
protein co-opts VEGF-A/neuropilin-1 receptor signaling to induce analgesia : PAIN …
VEGF targets the tumour cell
HL Goel, AM Mercurio - Nature Reviews Cancer, 2013 - nature.com
The function of vascular endothelial growth factor (VEGF) in cancer is not limited to
angiogenesis and vascular permeability. VEGF-mediated signalling occurs in tumour cells …
angiogenesis and vascular permeability. VEGF-mediated signalling occurs in tumour cells …
SARS-CoV-2 and the host cell: a tale of interactions
M Pizzato, C Baraldi, G Boscato Sopetto… - Frontiers in …, 2022 - frontiersin.org
The ability of a virus to spread between individuals, its replication capacity and the clinical
course of the infection are macroscopic consequences of a multifaceted molecular …
course of the infection are macroscopic consequences of a multifaceted molecular …
Inhibition of FGF‐FGFR and VEGF‐VEGFR signalling in cancer treatment
G Liu, T Chen, Z Ding, Y Wang, Y Wei, X Wei - Cell proliferation, 2021 - Wiley Online Library
The sites of targeted therapy are limited and need to be expanded. The FGF‐FGFR
signalling plays pivotal roles in the oncogenic process, and FGF/FGFR inhibitors are a …
signalling plays pivotal roles in the oncogenic process, and FGF/FGFR inhibitors are a …
Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer
Although blocking the binding of vascular endothelial growth factor (VEGF) to neuropilin-2
(NRP2) on tumor cells is a potential strategy to treat aggressive carcinomas, a lack of …
(NRP2) on tumor cells is a potential strategy to treat aggressive carcinomas, a lack of …