Objectives This review proposes case definitions and diagnostic considerations of systemic
disorders and conditions that affect the periodontal attachment apparatus. Importance …

The major mineralized tissues are bone and teeth, which share several mechanisms
governing their development and mineralization. This crossover includes the hormones that …

It is well established that alterations in phosphate metabolism have a profound effect on
hard and soft tissues of the oral cavity. The present-day clinical form of osteonecrosis of the …

Bone tissue engineering techniques are a promising alternative for the use of autologous
bone grafts to reconstruct bone defects in the oral and maxillofacial region. However, for …

Nanomaterials have unique and superior properties such as high surface area and
nanoscale size, makes them highly advanced and vital for rapid diagnosis and beneficial in …

Hypophosphatasia (HPP) is a rare, inherited, systemic, metabolic disorder caused by
autosomal recessive mutations or a single dominant-negative mutation in the gene …

X-linked hypophosphatemia (XLH) is a rare, hereditary, progressive musculoskeletal
disease that often causes pain and short stature, as well as decreased physical function …

Screening gene function in vivo is a powerful approach to discover novel drug targets. We
present high-throughput screening (HTS) data for 3 762 distinct global gene knockout (KO) …

Familial tumoral calcinosis (FTC)/hyperostosis‐hyperphosphatemia syndrome (HHS) is a
rare disorder caused by mutations in the genes encoding fibroblast growth factor‐23 …

Background Hypophosphatasia (HPP) is a rare inherited metabolic disease in which
mutations in the ALPL gene (encoding tissue‐nonspecific alkaline phosphatase) result in …