Background Antipsychotic treatment is associated with metabolic disturbance. However, the
degree to which metabolic alterations occur in treatment with different antipsychotics is …

Since the discovery of chlorpromazine (CPZ) in 1952, first-generation antipsychotics (FGAs)
have revolutionized psychiatric care in terms of facilitating discharge from hospital and …

The American Psychiatric Association Practice Guideline for the Treatment of Patients With
Schizophrenia seeks to reduce these substantial psychosocial and public health …

Objective There is some evidence that clozapine is significantly underutilised. Also,
clozapine use is thought to vary by country, but so far no international study has assessed …

Obesity is a multifactorial disease in which environmental conditions and several genes play
an important role in the development of this disease. Obesity is associated with …

Tardive dyskinesia (TD) risk with D2/serotonin receptor antagonists or D2 receptor partial
agonists (second‐generation antipsychotics, SGAs) is considered significantly lower than …

Schizophrenia is a debilitating psychiatric disorder, leading to both physical and social
morbidity. Despite its importance, the etiology of schizophrenia remains poorly understood …

Second generation antipsychotics (SGAs), such as clozapine, olanzapine, risperidone and
quetiapine, are among the most effective therapies to stabilize symptoms schizophrenia (SZ) …

Background Integrase strand-transfer inhibitor (INSTI)-based antiretroviral therapy (ART) is
recommended for human immunodeficiency virus (HIV) management. Although studies …

Excess deaths from cardiovascular disease are a major contributor to the significant
reduction in life expectancy experienced by people with schizophrenia. Important risk factors …